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非综合征性矢状缝早闭患者额外的鳞状缝融合及颅内体积分段情况

Additional squamosal suture synostosis and segmented intracranial volume in patients with non-syndromic sagittal synostosis.

作者信息

Leikola Junnu, Heliövaara Arja, Koivikko Mika, Koljonen Virve

机构信息

Cleft Palate and Craniofacial Center, Department of Plastic Surgery, Töölö Hospital, Helsinki University Central Hospital, P.O. Box 266, FI-00029, Helsinki, Finland.

Helsinki Medical Imaging Center, Department of Radiology, Helsinki University Central Hospital, Helsinki, Finland.

出版信息

Childs Nerv Syst. 2019 Feb;35(2):205-207. doi: 10.1007/s00381-018-04029-4. Epub 2019 Jan 7.

DOI:10.1007/s00381-018-04029-4
PMID:30617575
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6351507/
Abstract

PURPOSE

To evaluate the incidence of squamosal suture synostosis (SQS) in children with non-syndromic sagittal synostosis and to evaluate whether the additional SQS affects the intracranial volume (ICV).

METHODS

Thirty-four consecutive patients (23 boys) who had been operated by cranial vault remodelling because of sagittal synostosis were compared retrospectively from 3D-CT imaging data sets obtained from volumetric CT. The mean age of the patients at preoperative CT imaging was 0.48 (range 0.13-1.3) years. Mann-Whitney U test was used in the statistical analyses.

RESULTS

Sagittal synostosis was combined with SQS in four children (11.7%) but the additional SQS did not affect the ICV. SQS was unilateral in all children, two were located on the right and two on the left side. The length of the SQS varied between 4 and 27 mm. The children with SQS had a shorter sagittal suture synostosis length ratio (length of synostosis / total sagittal suture length × 100) than those without SQS.

CONCLUSIONS

The incidence of SQS in non-syndromic sagittal synostosis was 11.7% but SQS did not affect the ICV.

摘要

目的

评估非综合征性矢状缝早闭患儿鳞状缝早闭(SQS)的发生率,并评估额外的SQS是否影响颅内体积(ICV)。

方法

回顾性比较34例因矢状缝早闭接受颅盖重塑手术的连续患者(23例男孩),这些患者的数据来自容积CT获得的3D-CT成像数据集。术前CT成像时患者的平均年龄为0.48岁(范围0.13 - 1.3岁)。统计分析采用曼-惠特尼U检验。

结果

4例儿童(11.7%)的矢状缝早闭合并SQS,但额外的SQS未影响ICV。所有儿童的SQS均为单侧,2例位于右侧,2例位于左侧。SQS的长度在4至27毫米之间。有SQS的儿童矢状缝早闭长度比(早闭长度/矢状缝总长度×100)低于无SQS的儿童。

结论

非综合征性矢状缝早闭中SQS的发生率为11.7%,但SQS不影响ICV。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e22/6351507/fa5ef9ddf7c6/381_2018_4029_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e22/6351507/af16e88ab11c/381_2018_4029_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e22/6351507/fa5ef9ddf7c6/381_2018_4029_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e22/6351507/af16e88ab11c/381_2018_4029_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0e22/6351507/fa5ef9ddf7c6/381_2018_4029_Fig2_HTML.jpg

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本文引用的文献

1
Length of synostosis and segmented intracranial volume correlate with age in patients with non-syndromic sagittal synostosis.在非综合征性矢状缝早闭患者中,骨缝早闭的长度和分段颅内体积与年龄相关。
Childs Nerv Syst. 2018 Mar;34(3):511-515. doi: 10.1007/s00381-017-3628-2. Epub 2017 Oct 24.
2
Squamosal Craniosynostosis: Defining the Phenotype and Indications for Surgical Management.
Ann Plast Surg. 2017 Nov;79(5):458-466. doi: 10.1097/SAP.0000000000001170.
3
Minor Suture Fusion in Syndromic Craniosynostosis.综合征性颅缝早闭中的微小缝合融合
Plast Reconstr Surg. 2017 Sep;140(3):434e-445e. doi: 10.1097/PRS.0000000000003586.
4
Squamosal Suture Synostosis: Incidence, Associations, and Implications for Treatment.鳞状缝早闭:发病率、关联因素及对治疗的影响
J Craniofac Surg. 2017 Jul;28(5):1179-1184. doi: 10.1097/SCS.0000000000003603.
5
Squamous Suture Synostosis: A Review With Emphasis on Cranial Morphology and Involvement of Other Cranial Sutures.鳞状缝早闭:以颅骨形态学及其他颅骨缝受累情况为重点的综述
J Craniofac Surg. 2017 Jan;28(1):51-55. doi: 10.1097/SCS.0000000000003184.
6
The Significance of Squamosal Suture Synostosis.鳞状缝早闭的意义
J Craniofac Surg. 2016 Sep;27(6):1543-9. doi: 10.1097/SCS.0000000000002888.