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卢旺达农村地区医院剖宫产术后手术部位感染的发生率及预测因素。

Prevalence and predictors of surgical-site infection after caesarean section at a rural district hospital in Rwanda.

机构信息

Partners In Health/Inshuti Mu Buzima, Rwanda.

Department of Global Health and Social Medicine, Harvard Medical School, Boston, Massachusetts, USA.

出版信息

Br J Surg. 2019 Jan;106(2):e121-e128. doi: 10.1002/bjs.11060.

Abstract

BACKGROUND

There are few prospective studies of outcomes following surgery in rural district hospitals in sub-Saharan Africa. This study aimed to estimate the prevalence and predictors of surgical-site infection (SSI) following caesarean section at Kirehe District Hospital in rural Rwanda.

METHODS

Adult women who underwent caesarean section between March and October 2017 were given a voucher to return to the hospital on postoperative day (POD) 10 (±3 days). At the visit, a physician evaluated the patient for an SSI. A multivariable logistic regression model was used to identify risk factors for SSI, built using backward stepwise selection.

RESULTS

Of 729 women who had a caesarean section, 620 were eligible for follow-up, of whom 550 (88·7 per cent) returned for assessment. The prevalence of SSI on POD 10 was 10·9 per cent (60 women). In the multivariable analysis, the following factors were significantly associated with SSI: bodyweight more than 75 kg (odds ratio (OR) 5·98, 1·56 to 22·96; P = 0·009); spending more than €1·1 on travel to the health centre (OR 2·42, 1·31 to 4·49; P = 0·005); being a housewife compared with a farmer (OR 2·93, 1·08 to 7·97; P = 0·035); and skin preparation with a single antiseptic compared with a combination of two antiseptics (OR 4·42, 1·05 to 18·57; P = 0·043). Receiving either preoperative or postoperative antibiotics was not associated with SSI.

CONCLUSION

The prevalence of SSI after caesarean section is consistent with rates reported at tertiary facilities in sub-Saharan Africa. Combining antiseptic solutions for skin preparation could reduce the risk of SSI.

摘要

背景

在撒哈拉以南非洲的农村地区,关于农村地区医院手术后结果的前瞻性研究很少。本研究旨在评估卢旺达农村基里希区医院剖宫产术后手术部位感染(SSI)的发生率和预测因素。

方法

2017 年 3 月至 10 月间接受剖宫产术的成年女性收到一张凭证,可在术后第 10 天(±3 天)返回医院。在就诊时,医生会评估患者的 SSI 情况。使用向后逐步选择法构建多变量逻辑回归模型,以确定 SSI 的危险因素。

结果

在 729 名接受剖宫产术的女性中,有 620 名符合随访条件,其中 550 名(88.7%)返回接受评估。术后第 10 天 SSI 的发生率为 10.9%(60 名女性)。在多变量分析中,以下因素与 SSI 显著相关:体重超过 75kg(比值比(OR)5.98,1.56 至 22.96;P=0.009);前往医疗中心的旅行费用超过 1.1 欧元(OR 2.42,1.31 至 4.50;P=0.005);与农民相比是家庭主妇(OR 2.93,1.08 至 7.97;P=0.035);与使用两种消毒剂相比,单一消毒剂进行皮肤准备(OR 4.42,1.05 至 18.57;P=0.043)。接受术前或术后抗生素治疗与 SSI 无关。

结论

剖宫产术后 SSI 的发生率与撒哈拉以南非洲三级医疗机构报告的发生率一致。组合消毒剂进行皮肤准备可降低 SSI 的风险。

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