Dong Ruijiao, Liu Ruiyi, Gaffney Piers R J, Schaepertoens Marc, Marchetti Patrizia, Williams Christopher M, Chen Rongjun, Livingston Andrew G
Department of Chemical Engineering, Imperial College London, London, UK.
EPSRC UK National Mass Spectrometry Facility (NMSF), Swansea University Medical School, Swansea, UK.
Nat Chem. 2019 Feb;11(2):184. doi: 10.1038/s41557-019-0212-2.
In the version of this Article originally published, the authors inadvertently cited ref. 10 in two places in the first paragraph. They would like to clarify that it should not have been cited in the sentence that starts "Polymer chemists have employed strategies such as single monomer insertion..." as it mistakenly implied that the IEG+ method described in ref. 10 could not produce unimolecular polymers; it can do so, as was demonstrated in ref. 10. The authors would also like to clarify that ref. 10 should not have been cited in the sentence that starts "Moreover, solid-phase synthesis is generally difficult to scale up...", as it implied that ref. 10 uses solid-phase synthesis; it does not, and is a purely liquid-phase process. The citation of ref. 10 has now been removed from these two sentences, but has been included elsewhere in the first two paragraphs of the Article as follows. In the first paragraph, at the end of the sentence "In iterative synthesis, specific monomers are added one at a time, or as multiples, to the end of a growing polymer chain, then reaction debris is separated from the chain extended polymer, and the cycle is repeated using the next monomer in the sequence."; this sentence has been further amended to indicate multiple monomers can also be added. The reference has also been added to the end of the first sentence of the second paragraph, which starts "Consequently, liquid-phase iterative synthetic methods...", and in the third sentence of that paragraph, which now starts "For example, Johnson, Whiting...".
在本文最初发表的版本中，作者在第一段的两处不小心引用了参考文献10。他们想要澄清的是，在以“高分子化学家采用了诸如单单体插入……”开头的句子中不应该引用该文献，因为这错误地暗示了参考文献10中描述的IEG+方法不能生成单分子聚合物；实际上它是可以的，正如参考文献10中所证明的那样。作者还想澄清，在以“此外，固相合成通常难以扩大规模……”开头的句子中也不应该引用参考文献10，因为这暗示参考文献10使用固相合成；它并不使用，而是一个纯粹的液相过程。参考文献10的引用现已从这两句话中删除，但已包含在文章前两段的其他地方，如下所示。在第一段中，在“在迭代合成中，特定的单体一次添加一个，或多个，添加到正在生长的聚合物链的末端，然后将反应碎片与链延伸的聚合物分离，并使用序列中的下一个单体重复该循环。”这句话的末尾；这句话已进一步修改以表明也可以添加多个单体。该参考文献也已添加到第二段第一句的末尾，该句以“因此，液相迭代合成方法……”开头，以及该段的第三句，现在以“例如，约翰逊、怀廷……”开头。
