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电子处方:引入即时可选剂量以缩短急性内科病房使用抗生素的时间。

Electronic prescribing: introducing a stat optional dose to improve time to antibiotic on the acute medical unit.

作者信息

Jones Thomas Robert Edward, Nurse Kim

机构信息

Acute Medical Unit, County Durham and Darlington Foundation Trust, England, UK.

出版信息

BMJ Open Qual. 2018 Dec 19;7(4):e000292. doi: 10.1136/bmjoq-2017-000292. eCollection 2018.

Abstract

Darlington Memorial Hospital is a district general hospital in the North East of England. The acute medical unit (AMU) takes referrals from the emergency department and also direct from general practitioners (GPs) in the region. Research shows that early recognition and management of sepsis is key to improving outcomes and significantly decreases mortality. Having observed several cases of delayed sepsis management in patients referred from their GP, we aimed to improve time to antibiotic therapy in patients identified as having sepsis as per the National Institute for Health and Care Excellence 2016 NG51 sepsis guidelines. We analysed the time from admission to antibiotic administrations for patients referred to AMU via their GP with suspected sepsis. We found there was a significant delay between antibiotic prescribing and administration. Baseline data showed that only 36% of patients received a stat dose of antibiotic on admission. Results showed that those patients with a stat dose prescribed had a median time of 36 min from prescription to antibiotic compared with 98 min for those without. We introduced a stat antibiotic option with all antibiotic prescriptions on the electronic prescribing system, encouraging prescribers to administer a stat dose. Through focusing on antibiotic prescribing systems and practices over two PDSA cycles, we were able to improve the time from prescription to administration of antibiotics for patients with sepsis. We reduced the delay in antibiotic administration in patients with sepsis from 49 to 34 min, an improvement of 31% (15/49). The percentage of patients receiving a stat dose of antibiotics increased from 36% to 63%. While we acknowledge that there remains room for improvement with regards to antibiotic prescribing and sepsis management, we have made sustainable interventions with important improvements. E-prescribing systems must be evaluated and modified accordingly on a regular basis to ensure that they positively contribute to quality patient care and clinical practice.

摘要

达灵顿纪念医院是位于英格兰东北部的一家区综合医院。急性医疗单元(AMU)接收来自急诊科的转诊,也接收该地区全科医生(GP)的直接转诊。研究表明,脓毒症的早期识别和管理是改善治疗结果的关键,可显著降低死亡率。在观察到几例从全科医生转诊来的患者出现脓毒症管理延迟的情况后,我们旨在根据英国国家卫生与临床优化研究所2016年NG51脓毒症指南,缩短被确定为患有脓毒症患者的抗生素治疗时间。我们分析了通过全科医生转诊至AMU且疑似脓毒症患者从入院到使用抗生素的时间。我们发现抗生素处方开具和给药之间存在显著延迟。基线数据显示,只有36%的患者在入院时接受了一剂即服抗生素。结果表明,开具了即服剂量的患者从处方到使用抗生素的中位时间为36分钟,而未开具的患者为98分钟。我们在电子处方系统上为所有抗生素处方引入了即服抗生素选项,鼓励开处方者给予即服剂量。通过在两个计划-实施-检查-行动(PDSA)循环中关注抗生素处方系统和实践,我们得以缩短脓毒症患者从处方到使用抗生素的时间。我们将脓毒症患者抗生素给药延迟时间从49分钟缩短至34分钟,改善了31%(15/49)。接受一剂即服抗生素的患者比例从36%增至63%。虽然我们承认在抗生素处方开具和脓毒症管理方面仍有改进空间,但我们已经进行了可持续的干预并取得了重要改善。必须定期对电子处方系统进行评估和相应修改,以确保它们对优质患者护理和临床实践做出积极贡献。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4af8/6307570/c64c75ce1e74/bmjoq-2017-000292f01.jpg

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