Bloomfield S E, David D S, Cheigh J S, Kim Y, White R P, Stenzel K H, Rubin A L
Arch Intern Med. 1978 May;138(5):706-8.
Endophthalmitis occurred three months following completion of therapy for documented staphylococcal septicemia in two patients on long-term hemodialysis. The indolent course of the endophthalmitis, and its excellent response to systemic and subconjunctival antibiotics and subconjunctival and topical corticosteroid therapy, suggest the possibility that the acute fulminating clinical course of metastatic bacterial endophthalmitis may be modified in this population of patients. The reason for this modified clinical picture is probably the immune incompetence associated with uremia, which favors both the development of metastatic endophthalmitis as well as altering its clinical presentation. While funduscopic examination is suggested in all dialysis patients with eye complaints, this procedure becomes mandatory following episodes of sepsis.
两名长期接受血液透析的患者在确诊为葡萄球菌败血症并完成治疗三个月后发生了眼内炎。眼内炎病程进展缓慢，对全身及结膜下抗生素以及结膜下和局部皮质类固醇治疗反应良好，这表明在这类患者中，转移性细菌性眼内炎的急性暴发性临床病程可能会有所改变。这种改变的临床症状的原因可能是与尿毒症相关的免疫功能不全，这既有利于转移性眼内炎的发展，也会改变其临床表现。虽然建议对所有有眼部不适的透析患者进行眼底检查，但在发生败血症后，这一检查就成为必需。
