Ekema Ernest M
Immunohematology Reference Laboratory, American Red Cross, Greater Chesapeake and Potomac Region.
Immunohematology. 2018 Dec;34(4):158-160.
Cold-reactive autoantibodies can mask the presence of underlying clinically significant alloantibodies in a patient's plasma or serum. These autoantibodies are problematic when performing laboratory procedures such as ABO typing, red blood cell (RBC) crossmatching, antibody detection testing, and antibody identification. To avert the masking of clinically significant alloantibodies in a patient's plasma or serum, adsorption studies can be performed at 4°C using autologous RBCs if the patient has not been recently transfused.
冷反应性自身抗体可掩盖患者血浆或血清中潜在的具有临床意义的同种抗体。在进行诸如ABO血型鉴定、红细胞（RBC）交叉配血、抗体检测试验和抗体鉴定等实验室操作时，这些自身抗体就会成为问题。为避免掩盖患者血浆或血清中具有临床意义的同种抗体，如果患者近期未接受输血，可使用自身红细胞在4°C下进行吸附研究。
