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[混合培养中不同类型上皮的相互作用]

[Interaction of different types of epithelium in a mixed culture].

作者信息

Fetisova E K

出版信息

Ontogenez. 1988 Sep-Oct;19(5):481-6.

PMID:3062522
Abstract

Interaction of several lines of epithelial cells was studied in a mixed culture: FBT (bovine fetal trachea), MDSK (dog kidney), IAR-2 (rat liver), MPTR (SV-40 transformed mouse kidney). During mixed cultivation epithelia cells of different types were capable to force out each other from the substrate to full elimination. This capacity correlated with the pattern of cell contacts with the substrate. It is supposed that epithelial cells can form lamellae at the lower surfaces competing for substrate. Those cells which have lamellae with continuous marginal focal contacts and numerous focal contacts eliminate the cells having lamellae with few focal contacts.

摘要

在混合培养中研究了几类上皮细胞的相互作用

FBT(牛胎儿气管)、MDSK(狗肾)、IAR - 2(大鼠肝脏)、MPTR(SV - 40转化的小鼠肾)。在混合培养期间,不同类型的上皮细胞能够将彼此从基质上排挤出去直至完全消除。这种能力与细胞与基质的接触模式相关。据推测,上皮细胞可在其下表面形成薄片以竞争基质。那些具有连续边缘粘着斑和大量粘着斑的薄片的细胞会消除那些具有少量粘着斑的薄片的细胞。

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