Suppr超能文献

白内障手术期间输注右美托咪定后出现心动过缓导致心搏停止:右美托咪定诱发的白内障手术心搏停止

Bradycardia Leading to Asystole Following Dexmedetomidine Infusion during Cataract Surgery: Dexmedetomidine-Induced Asystole for Cataract Surgery.

作者信息

Aikaterini Amaniti, Ioannis Dalakakis, Dimitrios Gkinas, Konstantinos Sapalidis, Vasilios Grosomanidis, George Papazisis

机构信息

AHEPA University Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.

Laboratory of Pharmacology, Aristotle University of Thessaloniki, Thessaloniki, Greece.

出版信息

Case Rep Anesthesiol. 2018 Dec 5;2018:2896032. doi: 10.1155/2018/2896032. eCollection 2018.

Abstract

Dexmedetomidine is an elective alpha-2 adrenergic agonist, being used in anesthesia practice. It offers sedative, anxiolytic, analgesic, muscle relaxant, and sympathetic lytic properties. While respiratory effects are considered minor, there are important cardiovascular side effects with bradycardia and hypotension being the most common. This article presents a case of a patient, with significant comorbidities and polypharmacy, who was scheduled for cataract surgery under dexmedetomidine sedation. During the administration, severe hemodynamic deterioration was observed with bradycardia and hypotension leading to asystole. Cardiac arrest was successfully managed in accordance with the guidelines of the European Resuscitation Council. Despite the promising role of dexmedetomidine in anesthesia practice, the associated adverse effects cannot be ignored. For this reason it is obligatory to have the minimum mandatory monitoring in accordance with the safety and quality guidelines.

摘要

右美托咪定是一种选择性α-2肾上腺素能激动剂,用于麻醉实践。它具有镇静、抗焦虑、镇痛、肌肉松弛和交感神经阻滞作用。虽然呼吸影响被认为较小,但存在重要的心血管副作用,最常见的是心动过缓和低血压。本文介绍了一例有严重合并症和多种药物治疗史的患者,计划在右美托咪定镇静下进行白内障手术。给药期间,观察到严重的血流动力学恶化,伴有心动过缓和低血压导致心脏停搏。根据欧洲复苏委员会的指南,心脏骤停得到了成功处理。尽管右美托咪定在麻醉实践中具有前景,但相关的不良反应不容忽视。因此,必须按照安全和质量指南进行最低限度的强制监测。

相似文献

2
Bradycardia resulting in cardiac arrest in a critically ill patient receiving dexmedetomidine.
Trauma Case Rep. 2021 Oct 25;36:100548. doi: 10.1016/j.tcr.2021.100548. eCollection 2021 Dec.
3
Asystole-induced Bradycardia by Dexmedetomidine during Endoscopic Submucosal Dissection.
Intern Med. 2022 Aug 15;61(16):2457-2461. doi: 10.2169/internalmedicine.8813-21. Epub 2022 Feb 1.
6
Dexmedetomidine premedication attenuates ketamine-induced cardiostimulatory effects and postanesthetic delirium.
Anesthesiology. 1995 May;82(5):1117-25. doi: 10.1097/00000542-199505000-00005.
7
Dexmedetomidine use in general anaesthesia.
Curr Drug Targets. 2009 Aug;10(8):687-95. doi: 10.2174/138945009788982423.
8
Asystole in 2 Pediatric Patients During Dexmedetomidine Infusion.
J Pharm Pract. 2023 Feb;36(1):176-179. doi: 10.1177/08971900211027133. Epub 2021 Jun 24.
10
Initial experience with dexmedetomidine for diagnostic and interventional cardiac catheterization in children.
Paediatr Anaesth. 2007 Feb;17(2):109-12. doi: 10.1111/j.1460-9592.2006.02031.x.

引用本文的文献

2
Evaluation of the Relationship between Baseline Autonomic Tone and Haemodynamic Effects of Dexmedetomidine.
Pharmaceuticals (Basel). 2023 Feb 25;16(3):354. doi: 10.3390/ph16030354.
6
Asystole-induced Bradycardia by Dexmedetomidine during Endoscopic Submucosal Dissection.
Intern Med. 2022 Aug 15;61(16):2457-2461. doi: 10.2169/internalmedicine.8813-21. Epub 2022 Feb 1.

本文引用的文献

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验