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一名绝经后女性因分泌睾酮的卵巢间质瘤继发高雄激素血症并伴有听神经瘤。

Hyperandrogenism in a Postmenopausal Woman Secondary to Testosterone Secreting Ovarian Stromal Tumor with Acoustic Schwannoma.

作者信息

Gandrapu Bindu, Sundar Preeyanka, Phillips Brian

机构信息

Department of Internal Medicine, Berkshire Medical Center, Pittsfield, MA, USA.

Division Director, Department of Endocrinology, Berkshire Medical Center, Pittsfield, MA, USA.

出版信息

Case Rep Endocrinol. 2018 Dec 5;2018:8154513. doi: 10.1155/2018/8154513. eCollection 2018.

Abstract

Androgen-secreting ovarian neoplasms are rare ovarian tumors that present with hirsutism and virilization which may manifest as severe alopecia, deepening of voice, and clitoromegaly. Most often, ovarian tumors are found to be very small or even undetectable. In such cases, bilateral salpingo-oophorectomy should be performed after ruling out other causes of high androgens. We present a 63-year-old postmenopausal woman with clinically and radiologically undetectable testosterone-secreting ovarian tumor, which was later on detected on biopsy.

摘要

分泌雄激素的卵巢肿瘤是罕见的卵巢肿瘤,表现为多毛症和男性化,可能表现为严重脱发、声音变粗和阴蒂肥大。大多数情况下,卵巢肿瘤非常小甚至无法检测到。在这种情况下,排除其他高雄激素原因后应进行双侧输卵管卵巢切除术。我们报告一例63岁绝经后女性,临床和影像学检查均未发现分泌睾酮的卵巢肿瘤,后来活检时才检测到。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6657/6304522/053c51f2fa26/CRIE2018-8154513.001.jpg

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