Oladiran Oreoluwa, Nwosu Ifeanyi
Reading Hospital, Tower Health System, West Reading, PA, USA.
Leighton Hospital NHS Trust, Crewe, Cheshire, UK.
Case Rep Hematol. 2018 Dec 4;2018:9175360. doi: 10.1155/2018/9175360. eCollection 2018.
Acute lymphoblastic leukemia (ALL) is a heterogeneous group of lymphoid disorders characterized by monoclonal proliferation and expansion of immature lymphoid cells in the bone marrow, blood, and other organs. It commonly presents with nonspecific symptoms such as lethargy, easy bruising, and weight loss. In this article, we present the case of a 48-year-old male who presented to the hospital with painless jaundice resulting from pancreatic infiltration, initially thought to be due to pancreatic or hepatobiliary malignancy. He was later diagnosed with ALL by lymph node biopsy and peripheral blood flow cytometry immunophenotyping and was transferred to a cancer treatment centre for unilateral bone marrow biopsy and further management. Our case highlights the rare occurrence of pancreatic infiltration in ALL.
急性淋巴细胞白血病（ALL）是一组异质性的淋巴系统疾病，其特征为骨髓、血液及其他器官中未成熟淋巴细胞的单克隆增殖和扩增。它通常表现为乏力、易瘀斑和体重减轻等非特异性症状。在本文中，我们报告了一例48岁男性患者，该患者因胰腺浸润出现无痛性黄疸而入院，最初被认为是胰腺或肝胆恶性肿瘤所致。后来通过淋巴结活检和外周血流式细胞术免疫表型分析诊断为ALL，并被转至癌症治疗中心进行单侧骨髓活检及进一步治疗。我们的病例突出了ALL中胰腺浸润的罕见情况。
