McDowell Michael M, Chiang Michael C, Agarwal Nitin, Friedlander Robert M, Wecht Daniel A
Department of Neurological Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA, USA.
Heliyon. 2018 Dec 29;4(12):e01099. doi: 10.1016/j.heliyon.2018.e01099. eCollection 2018 Dec.
There is extensive debate on the role of fixed pressure shunts in the adult population. Most studies assessing fixed pressure valves do not consider the potential for changes in technique and management of shunts. We sought to examine the natural history of fixed pressure.
We conducted a retrospective chart review of 169 patients undergoing shunt placement by the senior author Daniel Wecht (DW). The etiology of shunt placement, shunt failure rates, and outcome data was assessed for each patient.
Overall, 126 patients underwent initial shunt placement. Thirty-three (26.2%) patients required at least one shunt revision during follow-up. The most common cause of first time revision was mechanical shunt malfunction (13, 39.4%), followed by infection (7, 21.2%), and shunt migration (6, 18.2%). Three patients (9.1%) required revision due to misplaced catheters. Underdrainage or overdrainage of shunts each resulted in revisions for 2 (6.1%) patients. The mean follow-up length was 28.1 ± 6.1 months.
Fixed pressure shunts failed primarily because of shunt malfunction and occurred most commonly in patients developing hydrocephalus as a result of hemorrhage or normal pressure hydrocephalus (NPH). The overall failure rate between these two groups was proportionally equivalent. Both overdrainage or underdrainage were found to be rare indications for revision.
关于成人中固定压力分流器的作用存在广泛争议。大多数评估固定压力阀的研究没有考虑分流技术和管理变化的可能性。我们试图研究固定压力的自然病程。
我们对资深作者丹尼尔·韦希特(DW)进行分流术的169例患者进行了回顾性病历审查。评估了每位患者的分流置入病因、分流失败率和结局数据。
总体而言,126例患者接受了初次分流置入。33例(26.2%)患者在随访期间至少需要进行一次分流修正。首次修正的最常见原因是机械性分流故障(13例,39.4%),其次是感染(7例,21.2%)和分流移位(6例,18.2%)。3例(9.1%)患者因导管位置不当需要修正。分流的引流不足或引流过度各导致2例(6.1%)患者进行修正。平均随访时间为28.1±6.1个月。
固定压力分流器失败主要是由于分流故障,最常发生在因出血或正常压力脑积水(NPH)而发生脑积水的患者中。这两组之间的总体失败率成比例相当。发现引流不足或引流过度都是罕见的修正指征。