a Department of Anesthesia, Osakafu Saiseikai Noe Hospital , Osaka City , Osaka , Japan.
J Dermatolog Treat. 2019 Nov;30(7):674-676. doi: 10.1080/09546634.2019.1568379. Epub 2019 Jun 19.
Several case reports and reviews support a relationship between atopic dermatitis (AD) and infective endocarditis (IE). Here, we present a case of severe AD suspected of causing IE. A 21-year-old man with severe AD was admitted to our hospital due to unidentified fever, syncope, and headache. He was diagnosed with IE with cerebral embolism and mitral regurgitation. Before elective cardiac surgery, he was subcutaneously administered dupilumab for 2 months to control AD. Dupilumab improved AD, and cardiac surgery was performed without complications. Dupilumab may be effective in AD cases as preparation for cardiac surgery.
一些病例报告和综述支持特应性皮炎（AD）和感染性心内膜炎（IE）之间的关系。在这里，我们报告了一例严重 AD 疑似引起 IE 的病例。一名 21 岁的男性患有严重 AD，因不明原因发热、晕厥和头痛而被收入我院。他被诊断为 IE 合并脑栓塞和二尖瓣反流。在择期心脏手术前，他接受了皮下注射度普利尤单抗治疗 2 个月以控制 AD。度普利尤单抗改善了 AD，心脏手术顺利进行，无并发症。度普利尤单抗可能对心脏手术前的 AD 病例有效。
