Kokot F, Kuska J
Nephrologische Klinik der Schlesischen Medizinischen Akademie in Katowice.
Z Urol Nephrol. 1988 Jun;81(6):359-66.
In the present paper the significance of non-immunological factors in the development and progression of nephropathies according to the hypothesis of Brenner et al. especially hemodynamic changes in the glomerula with glomerular hyperperfusion and/or hyperfiltration is discussed and therapeutic conclusions are made. The normalized glomerular pressure conditions (converting-enzyme inhibitors), a normalization of hyperglycemia in diabetics, a retention in the use of protein-rich diet and platelet-aggregation inhibitors, respectively, play a special part in the treatment of chronic nephropathies.
根据布伦纳等人的假说，本文讨论了非免疫因素在肾病发生和发展中的意义，尤其是肾小球高灌注和/或高滤过引起的肾小球血流动力学变化，并得出了治疗结论。标准化的肾小球压力条件（转换酶抑制剂）、糖尿病患者高血糖的正常化、分别保持富含蛋白质饮食的摄入以及使用血小板聚集抑制剂，在慢性肾病的治疗中发挥着特殊作用。
