儿童早发性戈勒姆-斯图特病并发乳糜胸：干扰素和双膦酸盐治疗后骨病变近乎完全消退。
A Child with Early-Onset Gorham-Stout Disease Complicated by Chylothorax: Near-Complete Regression of Bone Lesions with Interferon and Bisphosphonate Treatment.
机构信息
Pediatric Clinic, Azienda Ospedaliera Universitaria Integrata, Verona, Italy.
Pediatric Clinic, Azienda Ospedaliera Universitaria Integrata, Verona, Italy,
出版信息
Horm Res Paediatr. 2019;91(6):406-410. doi: 10.1159/000495364. Epub 2019 Jan 10.
PMID:30630178
Abstract
We report a case of Gorham-Stout disease (GSD) complicated by chylothorax and treated with a combination therapy with interferon and bisphosphonates. This treatment may be helpful in improving the usually unfavorable prognosis of GSD beginning with a chylothorax before 1 year of age, and in reducing bone lesions. Moreover, the use of bisphosphonates appears to be useful in treating pain.
摘要
我们报告了一例戈勒姆-斯图特病（GSD）合并乳糜胸的病例，并采用干扰素和双膦酸盐联合治疗。这种治疗方法可能有助于改善通常预后不良的 GSD，尤其是在 1 岁之前发生乳糜胸的情况下，并减少骨病变。此外，使用双膦酸盐似乎对治疗疼痛也有用。
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