Addai-Mensah Otchere, Annani-Akollor Max Efui, Fondjo Linda Ahenkorah, Sarbeng Kwadwo, Anto Enoch Odame, Owiredu Eddie-Williams, Arthur Shanice Nglokie
Department of Medical Laboratory Technology, Faculty of Allied Health Sciences, College of Health Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Department of Molecular Medicine, School of Medical Sciences, College of Health Sciences, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
J Trop Med. 2018 Dec 4;2018:5019215. doi: 10.1155/2018/5019215. eCollection 2018.
The World Health Organization (WHO) recommends the use of Insecticide Treated Bed-Nets and Intermittent Preventive Treatment (IPT) with Sulphadoxine-Pyrimethamine (SP) as interventions in curbing malaria during pregnancy. However, increasing evidence shows a gap in coverage where not all pregnant women receive the recommended SP dose. This study evaluated the factors influencing uptake of IPTp-SP among pregnant women in Kumasi, Ghana.
This cross-sectional study was conducted among 280 pregnant women attending the Kwame Nkrumah University of Science and Technology Hospital in Kumasi, Ghana. Validated structured questionnaires were administered to obtain sociodemographic, medical/reproductive information, and IPTp-SP uptake among participants. Statistical analyses were performed using IBM SPSS 25.0 statistics.
The mean age of respondents was 29.7±4.9 years. Of the 280 women interviewed, 74.6% attended the antenatal care (ANC) clinic at least four times with only 31.8% completing the recommended doses. Tertiary education [aOR=3.15, 95% CI (0.94 -10.97), and p=0.042] and ≥ 4 ANC visits [aOR=24.6, 95% CI (5.87-103.07), p<0.0001] had statistically significant higher odds of completing the recommended IPTp-SP dose. However, participants employed by the formal sector [aOR=0.28, 95% CI (0.09 - 0.79), p=0.016] and participants with more than four children [aOR=0.14, 95% CI (0.03 - 0.63), and p=0.011] had statistically significant lower odds of completing the recommended IPT dose.
ANC attendance is critical in IPTp uptake. The results emphasize the need for the Health Policy Makers in Kumasi to encourage pregnant women, especially women working in the formal sector and women having more than four children to patronize ANC attendance to ensure high coverage of the recommended IPTp dose.
世界卫生组织(WHO)建议使用经杀虫剂处理的蚊帐以及使用磺胺多辛 - 乙胺嘧啶(SP)进行间歇性预防治疗(IPT),作为孕期控制疟疾的干预措施。然而,越来越多的证据表明在覆盖范围上存在差距,并非所有孕妇都接受了推荐剂量的SP。本研究评估了影响加纳库马西孕妇接受孕期间歇性预防治疗 - 磺胺多辛 - 乙胺嘧啶(IPTp-SP)的因素。
这项横断面研究在加纳库马西夸梅·恩克鲁玛科技大学医院就诊的280名孕妇中进行。使用经过验证的结构化问卷来获取参与者的社会人口统计学、医疗/生殖信息以及IPTp-SP的接受情况。使用IBM SPSS 25.0统计学软件进行统计分析。
受访者的平均年龄为29.7±4.9岁。在接受访谈的280名女性中,74.6%至少四次前往产前保健(ANC)诊所就诊,只有31.8%完成了推荐剂量。高等教育程度[aOR = 3.15,95%置信区间(0.94 - 10.97),p = 0.042]以及四次及以上ANC就诊[aOR = 24.6,95%置信区间(5.87 - 103.07),p < 0.0001]在完成推荐的IPTp-SP剂量方面具有统计学显著更高的几率。然而,受雇于正规部门的参与者[aOR = 0.28,95%置信区间(0.09 - 0.79),p = 0.016]以及有四个以上孩子的参与者[aOR = 0.14,95%置信区间(0.03 - 0.63),p = 0.011]在完成推荐的IPT剂量方面具有统计学显著更低的几率。
ANC就诊对于IPTp的接受至关重要。结果强调库马西的卫生政策制定者需要鼓励孕妇,特别是在正规部门工作的女性以及有四个以上孩子的女性前往ANC就诊,以确保推荐的IPTp剂量有高覆盖率。