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Multiplexed Immunohistochemistry for Molecular and Immune Profiling in Lung Cancer-Just About Ready for Prime-Time?用于肺癌分子和免疫分析的多重免疫组织化学——即将迎来黄金时代?
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本文引用的文献

1
Cons: should immunotherapy be incorporated in the treatment of oncogene-driven lung cancer?反对观点:免疫疗法是否应纳入致癌基因驱动的肺癌治疗中?
Transl Lung Cancer Res. 2018 Sep;7(Suppl 3):S290-S293. doi: 10.21037/tlcr.2018.07.11.
2
Blood-based tumor mutational burden as a predictor of clinical benefit in non-small-cell lung cancer patients treated with atezolizumab.基于血液的肿瘤突变负担可预测接受阿替利珠单抗治疗的非小细胞肺癌患者的临床获益。
Nat Med. 2018 Sep;24(9):1441-1448. doi: 10.1038/s41591-018-0134-3. Epub 2018 Aug 6.
3
The Society for Immunotherapy of Cancer consensus statement on immunotherapy for the treatment of non-small cell lung cancer (NSCLC).癌症免疫治疗学会关于免疫治疗非小细胞肺癌(NSCLC)的共识声明。
J Immunother Cancer. 2018 Jul 17;6(1):75. doi: 10.1186/s40425-018-0382-2.
4
Immune reprogramming via PD-1 inhibition enhances early-stage lung cancer survival.通过 PD-1 抑制进行免疫重编程可提高早期肺癌的生存率。
JCI Insight. 2018 Jul 12;3(13):96836. doi: 10.1172/jci.insight.96836.
5
Neoadjuvant PD-1 Blockade in Resectable Lung Cancer.新辅助 PD-1 阻断治疗可切除性肺癌。
N Engl J Med. 2018 May 24;378(21):1976-1986. doi: 10.1056/NEJMoa1716078. Epub 2018 Apr 16.
6
Cancer immunotherapy using checkpoint blockade.使用免疫检查点阻断的癌症免疫疗法。
Science. 2018 Mar 23;359(6382):1350-1355. doi: 10.1126/science.aar4060. Epub 2018 Mar 22.
7
Non-small cell lung cancer treatment (r)evolution: ten years of advances and more to come.非小细胞肺癌治疗的(变)革:十年进展及未来展望
Ecancermedicalscience. 2017 Nov 30;11:787. doi: 10.3332/ecancer.2017.787. eCollection 2017.
8
Incidence and mortality of lung cancer: global trends and association with socioeconomic status.肺癌的发病率和死亡率:全球趋势及其与社会经济地位的关系。
Sci Rep. 2017 Oct 30;7(1):14300. doi: 10.1038/s41598-017-14513-7.
9
Hypermutated Circulating Tumor DNA: Correlation with Response to Checkpoint Inhibitor-Based Immunotherapy.高突变循环肿瘤 DNA:与基于检查点抑制剂免疫治疗反应的相关性。
Clin Cancer Res. 2017 Oct 1;23(19):5729-5736. doi: 10.1158/1078-0432.CCR-17-1439.
10
Epidemiology, incidence and mortality of lung cancer and their relationship with the development index in the world.全球肺癌的流行病学、发病率和死亡率及其与发展指数的关系。
J Thorac Dis. 2016 Jun;8(6):1094-102. doi: 10.21037/jtd.2016.03.91.

Early stage resectable non-small cell lung cancer: is neoadjuvant immunotherapy the right way forward?

作者信息

Chiari Rita, Sidoni Angelo, Metro Giulio

机构信息

Medical Oncology, Santa Maria della Misericordia Hospital, Azienda Ospedaliera di Perugia, Perugia, Italy.

Section of Anatomic Pathology and Histology, Department of Experimental Medicine, University of Perugia Medical School, Perugia, Italy.

出版信息

J Thorac Dis. 2018 Nov;10(Suppl 33):S3890-S3894. doi: 10.21037/jtd.2018.10.22.

DOI:10.21037/jtd.2018.10.22
PMID:30631508
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6297455/
Abstract
摘要