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一名14岁青少年患腺泡细胞囊腺瘤的罕见病例:病例报告

A Rare Case of Acinar Cell Cystadenoma in a 14-Year-Old Adolescent: A Case Report.

作者信息

Cosgrove Natalie, DiPalma Joan, Katz Douglas, Kowalski Thomas

机构信息

Division of Gastroenterology and Hepatology, Department of Internal Medicine, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania.

Division of Pediatric Gastroenterology, Department of Pediatrics, Nemours duPont, Philadelphia, Pennsylvania.

出版信息

Case Rep Pancreat Cancer. 2016 Jan 1;2(1):3-5. doi: 10.1089/crpc.2015.29009.nco. eCollection 2016.

DOI:10.1089/crpc.2015.29009.nco
PMID:30631807
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6319691/
Abstract

Acinar cell cystadenoma is a rare pancreatic cyst that has been described in several case reports. This lesion may be incidental or asymptomatic, occurs predominately in females, and has a mean age of onset in the fourth decade. A previously healthy 14-year-old male presented with abdominal pain. He was found to have a pancreatic cystic lesion on ultrasound and cross-sectional imaging. His diagnosis remained uncertain despite additional analysis, including endoscopic ultrasound with fine-needle aspiration. The patient underwent successful laparoscopic excision for definitive diagnosis and management with an unremarkable postoperative course. He was diagnosed with a multilocular acinar cell cystadenoma. Acinar cell cystadenoma is a rare pancreatic cyst whose true malignant potential is unknown. Although there are no formal recommendations for post-operative monitoring and the true risk of recurrence is unknown, we recommended every other year magnetic resonance imaging/magnetic resonance cholangiopancreatography for postresection surveillance for this patient due to the theoretical risk of recurrence with malignant transformation.

摘要

腺泡细胞囊腺瘤是一种罕见的胰腺囊肿,已有多篇病例报告对其进行过描述。该病变可能是偶然发现或无症状的,主要发生于女性,平均发病年龄在40岁左右。一名既往健康的14岁男性因腹痛就诊。超声及断层成像检查发现他有胰腺囊性病变。尽管进行了包括超声内镜引导下细针穿刺活检在内的进一步分析,其诊断仍不明确。该患者接受了成功的腹腔镜切除术以明确诊断并进行治疗,术后恢复过程顺利。他被诊断为多房性腺泡细胞囊腺瘤。腺泡细胞囊腺瘤是一种罕见的胰腺囊肿,其真正的恶性潜能尚不清楚。虽然对于术后监测没有正式的建议,且真正的复发风险也未知,但鉴于存在恶变复发的理论风险,我们建议该患者术后每隔一年进行磁共振成像/磁共振胰胆管造影检查以进行随访监测。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5cf0/6319691/eb38233744ac/fig-3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5cf0/6319691/e1b0f4004651/fig-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5cf0/6319691/417b0e699507/fig-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5cf0/6319691/eb38233744ac/fig-3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5cf0/6319691/e1b0f4004651/fig-1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5cf0/6319691/417b0e699507/fig-2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5cf0/6319691/eb38233744ac/fig-3.jpg

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本文引用的文献

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Am J Surg Pathol. 2013 Sep;37(9):1329-35. doi: 10.1097/PAS.0b013e3182a1ad72.
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胰腺腺泡囊腺瘤:10 例临床病理研究,包括多房性病变伴壁结节。
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Acinar cell cystadenoma of the pancreas in a 9-year-old boy.胰腺腺泡细胞囊腺瘤,见于 9 岁男童。
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Acinar cell cystadenoma of the pancreas: a new entity?胰腺腺泡细胞囊腺瘤:一种新的实体?
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