在开放式乳突根治术中应用羊膜覆盖乳突腔。
Application of amniotic membrane for covering mastoid cavity in canal wall down mastoidectomy.
作者信息
Faramarzi Mohammad, Kaboodkhani Reza, Roosta Sareh, Azarpira Negar, Shishegar Mahmood, Bahranifard Hajar
机构信息
Otolaryngology Research Center, Department of Otolaryngology, Shiraz University of Medical Sciences, Shiraz, Iran.
Transplant Research Centre, Shiraz University of Medical Sciences, Shiraz, Iran.
出版信息
Laryngoscope. 2019 Jun;129(6):1453-1457. doi: 10.1002/lary.27638. Epub 2019 Jan 10.
OBJECTIVE
Prevention of granulation tissue formation and acceleration of epithelialization of the mastoid cavity in canal wall down (CWD) mastoidectomy by use of amniotic membrane (AM) as a biologic dressing.
STUDY DESIGN
Prospective and randomized study.
METHODS
During CWD mastoidectomy, an inferiorly base musculoperiosteal flap was rotated into the cavity. In order to coverage of this flap, the AM (75 ears) or the temporalis fascia (control group, 73 ears) was used. The times for mastoid cavity epithelialization were compared in both groups.
RESULTS
In the AM group, duration of complete epithelialization of the cavity was 41.4 ± 7.7 days, whereas in the control group it was 59.2 ± 9.1 days. Duration of time for complete epithelialization in the AM group was shorter than in the control group, which was significant (P < 0.0001).
CONCLUSION
The use of AM in CWD mastoidectomy is beneficial in minimizing postoperative epithelialization time.
LEVEL OF EVIDENCE
1b Laryngoscope, 129:1453-1457, 2019.
目的
通过使用羊膜（AM）作为生物敷料，预防乳突根治术（CWD）中肉芽组织形成并加速乳突腔上皮化。
研究设计
前瞻性随机研究。
方法
在CWD乳突根治术中，将一块底部向下的肌骨膜瓣旋转至乳突腔内。为覆盖该瓣，使用AM（75耳）或颞肌筋膜（对照组，73耳）。比较两组乳突腔上皮化的时间。
结果
AM组乳突腔完全上皮化的持续时间为41.4±7.7天，而对照组为59.2±9.1天。AM组完全上皮化的时间短于对照组，差异有统计学意义（P<0.0001）。
结论
在CWD乳突根治术中使用AM有利于缩短术后上皮化时间。
证据级别
1b《喉镜》，2019年，第129卷：1453 - 1457页
Zotero 插件