尿道憩室内的原发性小细胞神经内分泌肿瘤。
Primary Small Cell Neuroendocrine Tumor Within a Urethral Diverticulum.
机构信息
Department of Obstetrics and Gynecology, Saint Louis University School of Medicine, and Saint Louis University School of Medicine, St. Louis, Missouri.
出版信息
Obstet Gynecol. 2019 Feb;133(2):308-311. doi: 10.1097/AOG.0000000000003054.
BACKGROUND
Primary small cell neuroendocrine carcinoma of the urinary tract is a very rare cancer, accounting for fewer than 0.5% of urinary tract tumors. These are aggressive neoplasms with high rates of metastases. Urethral diverticula can be found in up to 6% of women.
CASE
A 31-year-old woman presented with a clear vaginal discharge and an anterior vaginal wall mass that was thought to be a recurrent cyst. After surgical dissection, she was noted to have a urethral diverticulum with a solid nodule at the base. Final pathology showed a high-grade small cell neuroendocrine carcinoma.
CONCLUSION
Malignancy in a urethral diverticulum can occur in young patients. Clinicians should be aware of this possibility when choosing to manage urethral lesions expectantly.
背景
原发性尿路小细胞神经内分泌癌是一种非常罕见的癌症，占尿路肿瘤的比例不到 0.5%。这些是侵袭性肿瘤，转移率很高。尿道憩室在多达 6%的女性中可以发现。
病例
一名 31 岁女性因阴道清亮分泌物和前阴道壁肿块就诊，肿块被认为是复发性囊肿。手术切开后，发现患者的尿道憩室底部有一个实性结节。最终的病理检查显示为高级别小细胞神经内分泌癌。
结论
年轻患者的尿道憩室也可能发生恶性肿瘤。当选择期待性地治疗尿道病变时，临床医生应该意识到这种可能性。
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