Purcaru Monica Ana Paraschiva, Repanovici Angela, Nedeloiu Tiberiu
Department of Mathematics and Informatics, Faculty of Mathematics and Informatics, Transilvania University of Brasov, 500036 Brasov, Romania.
Department of Product Design, Mechatronics and Environment, Faculty of Product Design and Environment, Transilvania University of Brasov, 500036 Brasov, Romania.
J Clin Med. 2019 Jan 9;8(1):65. doi: 10.3390/jcm8010065.
The study was performed at Brasov County Hospital, in the Internal Medicine, Diabetes, Gastroenterology and Cardiology Wards with the collaboration of Transylvania University of Brasov, as a study approved by the Ethical Board of the university. The study aimed at assessing the connection between the anthropometric parameters of abdominal adiposity (measured by means of an original experiment designed to determine the curvature of the thoracic-abdominal adiposity for the patients and processed by help of a mathematical model based upon Bezier curves geometry) and the fat load of the liver (assessed by ultrasound by measuring the diameters of both hepatic lobes) for the patients diagnosed with Non-Alcoholic Fatty Liver Disease (NAFLD). The existence of ten types of thoracic-abdominal curves profiles were statistically analyzed in order to evaluate in a simple manner the liver size in NAFLD. The method of diagnosis is based on an easily reproduced experiment, it is original, innovative, non-invasive, and cost-effective. Can be implemented anywhere in the world, there is no need for investment, only for determining the profile of the belly.
该研究在布拉索夫县医院的内科、糖尿病科、胃肠病科和心脏病科病房进行，与布拉索夫特兰西瓦尼亚大学合作，是一项经该大学伦理委员会批准的研究。该研究旨在评估腹部肥胖的人体测量参数（通过一项原始实验测量，该实验旨在确定患者胸腹肥胖的曲率，并借助基于贝塞尔曲线几何的数学模型进行处理）与被诊断为非酒精性脂肪性肝病（NAFLD）患者的肝脏脂肪负荷（通过超声测量两个肝叶的直径来评估）之间的联系。对十种类型的胸腹曲线轮廓进行了统计分析，以便以简单的方式评估NAFLD患者的肝脏大小。诊断方法基于一个易于重复的实验，具有原创性、创新性、非侵入性且成本效益高。可在世界任何地方实施，无需投资，仅需确定腹部轮廓。
