Department of Biochemistry and Biotechnology, State University of Londrina, P.O. Box 10.011, Londrina 86057-970, Paraná, Brazil.
Department of Pathological Sciences, State University of Londrina, P.O. Box 10.011, Londrina 86057-970, Paraná, Brazil.
Toxins (Basel). 2019 Jan 10;11(1):33. doi: 10.3390/toxins11010033.
Brazil is one of the world's largest corn producers and is a leader in exportation. Due to intense globalization, corn may be commercialized worldwide and the issue concerning the safety of corn-based products has become a topic of widespread international interest. Dietary exposure evaluation is a relevant criterion for mycotoxin risk assessment. Thus, human exposure to fumonisins were assessed for corn grain and its derivatives (endosperm, cornmeal, and grits; n = 320) sampled from one of the large-scale corn processing plants in Brazil. The total probable daily intake (PDI) for fumonisins in Brazil was 96.9 ng kg body weight day, which corresponds to 5% of the provisional maximum tolerable daily intake (PMTDI) of 2000 ng kg b.w. day for fumonisins. In countries that import Brazilian corn, the total PDI is lower in European countries (from 35.7 to 177 ng kg b.w. day) and higher in Angola (1553 ng kg b.w. day). Taking into account that dietary exposure in populations in Brazil and importing countries was low, the corn-based products were safe for human consumption regarding fumonisins, even for regions with high corn consumption.
巴西是世界上最大的玉米生产国之一，也是玉米出口的领导者。由于全球化的激烈竞争，玉米可能在全球范围内商业化，玉米制品的安全性问题已成为国际关注的热点话题。膳食暴露评估是真菌毒素风险评估的一个相关标准。因此，对巴西一家大型玉米加工厂生产的玉米谷物及其衍生物（胚乳、玉米粉和粗磨玉米）（n = 320）中的伏马菌素进行了人类暴露评估。巴西人对伏马菌素的总可能每日摄入量（PDI）为 96.9ng/kg 体重/天，相当于暂定最大耐受每日摄入量（PMTDI）的 5%，即 2000ng/kg b.w.天。在进口巴西玉米的国家中，欧洲国家的总 PDI 较低（35.7 至 177ng/kg b.w.天），而安哥拉较高（1553ng/kg b.w.天）。考虑到巴西和进口国人群的膳食暴露量较低，即使在玉米消费较高的地区，玉米制品也可安全食用，不会摄入伏马菌素。
