Boeryd B, Nilsson T, Lindholm L, Lange S, Hallgren B, Ställberg G
Eur J Immunol. 1978 Sep;8(9):678-80. doi: 10.1002/eji.1830080914.
In mice, the plaque-forming cell response to sheep red blood cells was stimulated by a mixture of methoxy-substituted glycerol ethers isolated from Greenland shark liver oil and by synthetic 1-0-(2-methoxyhexadecyl)-glycerol, given in the diet. In preliminary experiments, this synthetic compound also increased the ability of parental spleen cells to induce graft-vs.-host reactions in F1 hybrid mice. Glycerol ethers occur in the bone marrow fat of mammals and in the membrane phospholipids. It is postulated that the methoxy-substituted glycerol ethers supplied in the diet may stimulate the bone marrow and/or may be incorporated into membrane lipids, thereby changing the structure and function of the membranes.
在小鼠中，从格陵兰鲨肝油中分离出的甲氧基取代甘油醚混合物以及饮食中添加的合成1-0-(2-甲氧基十六烷基)-甘油，可刺激对绵羊红细胞的噬斑形成细胞反应。在初步实验中，这种合成化合物还增强了亲代脾细胞在F1杂种小鼠中诱导移植物抗宿主反应的能力。甘油醚存在于哺乳动物的骨髓脂肪和膜磷脂中。据推测，饮食中提供的甲氧基取代甘油醚可能刺激骨髓和/或可能掺入膜脂中，从而改变膜的结构和功能。
