Porubsky Caitlin F, Combs Angela, Buckley Christopher, Goodman Marcus B
Department of Dermatology, Philadelphia College of Osteopathic Medicine, Roswell, Georgia.
Department of Dermatopathology, Global Pathology Laboratory Services, Miami Lakes, Florida.
J Cutan Pathol. 2019 Apr;46(4):297-300. doi: 10.1111/cup.13421. Epub 2019 Feb 10.
Medallion-like dermal dendrocyte hamartoma is a rare congenital lesion that is more commonly seen in females. It often presents at birth on the neck or upper trunk as a well-circumscribed, atrophic patch with wrinkling of the overlying skin. Clinically, the differential diagnosis includes atrophoderma, anetoderma, and congenital atrophic dermatofibrosarcoma protuberans. Histologic findings show epidermal atrophy and dermal spindle cell proliferation that is CD34 positive, along with Factor XIIIa in the original reports. Due to this CD34 positivity, another name for the lesion is plaque-like CD34+ dermal fibroma. We present a unique patient case as he is male and the lesion is located on his abdomen. Further reports and studies need to be done for thorough understanding of this neoplasm.
奖章样真皮树突状细胞错构瘤是一种罕见的先天性病变，更常见于女性。它通常在出生时出现在颈部或上躯干，表现为边界清晰的萎缩性斑块，其上覆皮肤有皱纹。临床上，鉴别诊断包括皮肤萎缩症、皮肤松弛症和先天性萎缩性隆突性皮肤纤维肉瘤。组织学表现为表皮萎缩和真皮梭形细胞增殖，最初的报告显示其CD34阳性，同时伴有因子 XIIIa 阳性。由于这种CD34阳性，该病变的另一个名称是斑块样CD34 + 真皮纤维瘤。我们报告了一例独特的病例，患者为男性，病变位于腹部。需要进一步的报告和研究以全面了解这种肿瘤。
