Suppr超能文献

儿童细支气管炎——我们的选择明智吗?

Bronchiolitis in children - do we choose wisely?

作者信息

Kusak Beata, Grzesik Emilia, Konarska-Gabryś Kaja, Pacek Zofia, Piwowarczyk Barnaba, Lis Grzegorz

机构信息

Department of Pediatrics, Chair of Pediatrics, Jagiellonian University Medical College, Krakow, Poland.

出版信息

Dev Period Med. 2018;22(4):323-328. doi: 10.34763/devperiodmed.20182204.323328.

Abstract

OBJECTIVE

Aim: The aim of our study was to evaluate the adherence to the 2014 American Academy of Pediatrics guidelines for bronchiolitis.

PATIENTS AND METHODS

Material and methods: The study measured the utility of diagnostic and therapeutic procedures in children with the first episode of bronchiolitis in their lives hospitalized at the University Children's Hospital in Krakow, Poland, between September 2014 and March 2015. The results were compared with the achievable benchmarks of care (ABCs) for hospitalized children with bronchiolitis. Hospital performance was measured by five clinical indicators: chest X-ray utilization, viral testing implementation, steroids, antibiotics and bronchodilator prescriptions. Odds ratios (OR) with 95% confidence intervals (95%CI) were calculated for comparisons between hospital performance and ABCs.

RESULTS

Results: There were 214 children in the study group (56% were boys). Chest X-ray was performed in 95% of the children, while ABCs indicate 32.4% (OR=42; 95%CI [30-58]); viral testing in 67.9% children, whereas ABCs indicate 0.6% (OR=350; 95%CI [155-790]). Steroids were prescribed in 62% of the patients (ABCs=6.4%; OR=24; 95%CI [18-31]), similarly antibiotics in 62% (ABCs=18.5%; OR=20; 95%CI [15-25]), bronchodilators were administered in 86% patients (ABCs=18.9%; OR=27; 95%CI [21-34]). All the analyzed procedures were used dozens of times more often than suggested by ABCs (the difference is highly statistically significant).

CONCLUSION

Conclusions: Overuse of ineffective procedures and therapies in bronchiolitis remains common, with overuse of chest X-rays, viral testing, prescriptions of bronchodilators, corticosteroids and antibiotics. We should focus our efforts on strategies aimed at decreasing the procedures that have no benefit for children with bronchiolitis.

摘要

目的

本研究的目的是评估对2014年美国儿科学会毛细支气管炎指南的遵循情况。

患者与方法

本研究衡量了2014年9月至2015年3月期间在波兰克拉科夫大学儿童医院住院的首次患毛细支气管炎的儿童诊断和治疗程序的效用。将结果与住院毛细支气管炎患儿可实现的护理基准(ABCs)进行比较。通过五个临床指标衡量医院的表现:胸部X光检查的使用、病毒检测的实施、类固醇、抗生素和支气管扩张剂的处方。计算医院表现与ABCs之间比较的比值比(OR)及95%置信区间(95%CI)。

结果

研究组有214名儿童(56%为男孩)。95%的儿童进行了胸部X光检查,而ABCs显示为32.4%(OR = 42;95%CI [30 - 58]);67.9%的儿童进行了病毒检测,而ABCs显示为0.6%(OR = 350;95%CI [155 - 790])。62%的患者使用了类固醇(ABCs = 6.4%;OR = 24;95%CI [18 - 31]),同样62%的患者使用了抗生素(ABCs = 18.5%;OR = 20;95%CI [15 - 25]),86%的患者使用了支气管扩张剂(ABCs = 18.9%;OR = 27;95%CI [21 - 34])。所有分析的程序使用频率都比ABCs建议的高出数十倍(差异具有高度统计学意义)。

结论

毛细支气管炎中无效程序和治疗的过度使用仍然很常见,包括胸部X光检查、病毒检测、支气管扩张剂、皮质类固醇和抗生素的过度使用。我们应致力于采取策略,减少对毛细支气管炎患儿无益的程序。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ad69/8522821/87ad08138477/jmotherandchild-22-323-g001.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验