Kurek Łukasz, Jabłoński Krzysztof, Góralska Natalia, Żuchlińska Joanna, Stelmaszczyk Łukasz, Różanowski Paweł
Katedra Anatomii, Collegium Medicum, Uniwersytet Warmińsko-Mazurski w Olsztynie, Polska, Klinika Ginekologii i Położnictwa, Collegium Medicum, Uniwersytet Warmińsko-Mazurski w Olsztynie, Polska.
Klinika Ginekologii i Położnictwa, Collegium Medicum, Uniwersytet Warmińsko-Mazurski w Olsztynie, Polska.
Dev Period Med. 2018;22(4):390-395. doi: 10.34763/devperiodmed.20182204.390395.
Malignant tumors of the ovary are characterized by late detection which is the chief factor responsible for their poor prognosis. Almost 70% of ovarian cancers are diagnosed at clinical stage III or IV. At present, effective methods for early detection of ovarian cancer are lacking. One accepted approach to reduce the risk of ovarian cancer is bilateral salpingo-oophorectomy. However, it is increasingly widely believed that even a more limited surgery of bilateral salpingectomy may be also used prophylactically as an effective means to reduce cancer risk. The procedure is based on extensive anatomopathological research on the origins of malignant cells in ovarian cancer. There is already ample scientific evidence that in a high proportion of cases the primary site of neoplastic transformation is the distal segment of the fallopian tube, from which malignant cells migrate to the ovary. However, long-term studies demonstrating the effectiveness of prophylactic salpingectomy for ovarian cancer are required. This article summarizes the benefits and disadvantages of the procedure based on currently available literature.
卵巢恶性肿瘤的特点是发现较晚，这是其预后不良的主要因素。几乎70%的卵巢癌在临床III期或IV期被诊断出来。目前，缺乏有效的卵巢癌早期检测方法。一种公认的降低卵巢癌风险的方法是双侧输卵管卵巢切除术。然而，越来越多的人广泛认为，即使是更有限的双侧输卵管切除术也可作为预防性手术，作为降低癌症风险的有效手段。该手术基于对卵巢癌恶性细胞起源的广泛解剖病理学研究。已经有充分的科学证据表明，在很大一部分病例中，肿瘤转化的原发部位是输卵管远端，恶性细胞从那里迁移到卵巢。然而，需要长期研究来证明预防性输卵管切除术对卵巢癌的有效性。本文根据现有文献总结了该手术的利弊。
