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黑色素瘤检测方法和高风险个体皮肤监测方法:澳大利亚新临床实践。

Methods of melanoma detection and of skin monitoring for individuals at high risk of melanoma: new Australian clinical practice.

机构信息

Victorian Melanoma Service, Alfred Hospital, Melbourne, VIC.

Armadale Dermatology, Melbourne, VIC.

出版信息

Med J Aust. 2019 Jan;210(1):41-47. doi: 10.5694/mja2.12033. Epub 2018 Dec 2.

DOI:10.5694/mja2.12033
PMID:30636296
Abstract

INTRODUCTION

The evidence-based national clinical practice guidelines for the management of cutaneous melanoma published in 2008 are currently being updated. This article summarises the findings from multiple chapters of the guidelines on different methods of melanoma detection and of monitoring the skin for patients at high risk of melanoma. Early detection of melanoma is critical, as thinner tumours are associated with enhanced survival; therefore, strategies to improve early detection are important to reduce melanoma-related mortality.

MAIN RECOMMENDATIONS

Clinicians who perform skin examinations for the purpose of detecting skin cancer should be trained in and use dermoscopy. The use of short term sequential digital dermoscopy imaging to detect melanomas that lack dermoscopic features of melanoma is recommended to assess individual melanocytic lesions of concern. The use of long term sequential digital dermoscopy imaging to detect melanomas that lack dermoscopic features of melanoma is recommended to assess individual or multiple melanocytic lesions for routine surveillance of high risk patients. The use of total body photography should be considered in managing patients at increased risk for melanoma, particularly those with high naevus counts and dysplastic naevi. There is insufficient evidence to recommend the routine use of automated instruments for the clinical diagnosis of primary melanoma.

MANAGEMENT OVERVIEW

Determining the relative indications for each diagnostic method and how each method should be introduced into the surveillance of a patient requires careful consideration and an individualised approach.

摘要

简介

2008 年发布的针对皮肤黑色素瘤管理的循证临床实践指南正在进行更新。本文总结了指南中多个章节关于不同黑色素瘤检测方法和高危人群皮肤监测的发现。早期发现黑色素瘤至关重要,因为较薄的肿瘤与生存改善相关;因此,改善早期检测的策略对于降低黑色素瘤相关死亡率非常重要。

主要建议

为了检测皮肤癌而进行皮肤检查的临床医生应接受并使用皮肤镜检查方面的培训。推荐使用短期连续数字皮肤镜成像来检测缺乏黑色素瘤皮肤镜特征的黑色素瘤,以评估单个可疑黑素细胞病变。推荐使用长期连续数字皮肤镜成像来检测缺乏黑色素瘤皮肤镜特征的黑色素瘤,以评估单个或多个黑素细胞病变,用于高危患者的常规监测。应考虑对有较高黑色素瘤风险的患者进行全身摄影,尤其是那些痣数量多和发育不良痣的患者。没有足够的证据推荐常规使用自动化仪器进行原发性黑色素瘤的临床诊断。

管理概述

确定每种诊断方法的相对适应证以及每种方法应如何引入患者的监测中,需要仔细考虑并采取个体化的方法。

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