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皮肤电反应作为一种简单的生理学实验室教学工具——交感神经兴奋的替代指标

Galvanic Skin Response as a Simple Physiology Lab Teaching Tool- An Alternative Indicator of Sympathetic Arousal.

作者信息

Nepal O, Jha R K, Bhattarai A, Khadka P, Kapoor B K

机构信息

Department of Physiology, Kathmandu University School of Medical Sciences, Dhulikhel, Kavre, Nepal.

出版信息

Kathmandu Univ Med J (KUMJ). 2018 Apr-Jun;16(62):156-160.

Abstract

Background Sympathetic arousal response due to rewarding emotion may not be considered threat to the well-being but such arousal response evoked by fear or punishment can be stressful. When such changes are recorded in lab as biological signals, induced with appropriate stimulus, the observed response may serve as a good indicator of homeostatic alteration. In this study, skin conductance was utilized to record sympathetic response for cognitive load, by application of simple subtraction task. Objective To detect sympathetic arousal by utilization of galvanic skin response during mental arithmetic task. Method Total of eighty two subjects, forty two female and forty male participated in the study. Twenty two subjects were provided mental task to record skin conductance. In sixty subjects, galvanic skin response, pulse rate, respiratory rate and temperature were recorded by appropriate transducers to obtain baseline and task response to detect differential recordings. Subjects performed the mental exercise of arithmetic task (MAT) with transducer placed in upper limbs. Mean of averages for respective variables were statistically calculated from obtained recordings. Result For measured galvanic skin response, 57 subjects showed increased skin conductance (rise in amplitude) whereas, 25 subjects had no rise in amplitude ("A peak") while performing the mental arithmetic task, when compared to control recording. However, in 20 subjects, pulse rate and respiratory rate showed significant rise though, the change in the skin conductance was not significant. Conclusion Galvanic skin response is useful for demonstration of sympathetic activation induced by simple mental subtraction task, and can be utilized along with vital parameters mentioned in this study to discuss in vivo variation that exist as differential for core and superficial sympathetic outflow among individuals.

摘要

背景 因愉悦情绪引起的交感神经唤醒反应可能不被视为对健康的威胁,但由恐惧或惩罚引发的这种唤醒反应可能会产生压力。当在实验室中通过适当刺激将这些变化记录为生物信号时,观察到的反应可能是内稳态改变的良好指标。在本研究中,通过应用简单减法任务,利用皮肤电导率记录认知负荷下的交感神经反应。

目的 利用心算任务期间的皮肤电反应检测交感神经唤醒。

方法 共有82名受试者参与研究,其中42名女性,40名男性。22名受试者接受心理任务以记录皮肤电导率。在60名受试者中,通过适当的传感器记录皮肤电反应、脉搏率、呼吸率和体温,以获取基线和任务反应,以检测差异记录。受试者在上肢放置传感器的情况下进行心算任务(MAT)的心理练习。从获得的记录中统计计算各变量的平均值。

结果 对于测量的皮肤电反应,与对照记录相比,57名受试者在心算任务期间皮肤电导率增加(幅度上升),而25名受试者的幅度没有上升(“峰值”)。然而,在20名受试者中,脉搏率和呼吸率显著上升,尽管皮肤电导率的变化不显著。

结论 皮肤电反应有助于证明简单心理减法任务诱导的交感神经激活,并且可以与本研究中提到的重要参数一起用于讨论个体之间核心和浅表交感神经输出差异存在的体内变化。

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