Bajracharya B, Poudel P, Bajracharya D, Bhattacharyya S, Shakya P
Department of Oral Pathology, Kantipur Dental College, Basundhara, Kathmandu, Nepal.
Department of Oral Surgery, Peoples Dental College, Shorakhutte, Kathmandu, Nepal.
Kathmandu Univ Med J (KUMJ). 2018 Apr-Jun;16(62):201-203.
Eosinophilic Granuloma is the mildest and localized form of Langerhans Cell Histiocytosis and is characterized by clonal proliferation of Langerhans cells. It is a rare disease, accounting for less than 1% of all the osseous neoplasms. It has predilection for the axial skeleton and incidence in jaws is just 7.9%. It lacks pathognomonic clinical and radiographic trait and hence is difficult to make a correct diagnosis without histopathological and immunohistochemical examination. This report describes a case of Eosinophilic Granuloma of mandible in 30 years old male who presented with complain of unhealed extraction wound and was clinically diagnosed as chronic suppurative osteomyelitis. The final diagnosis of Eosinophilic Granuloma was made only after histopathological and immunohistochemical evaluations.
嗜酸性肉芽肿是朗格汉斯细胞组织细胞增生症最轻微的局限性形式，其特征为朗格汉斯细胞的克隆性增殖。它是一种罕见疾病，占所有骨肿瘤的比例不到1%。它好发于中轴骨骼，在颌骨中的发病率仅为7.9%。它缺乏特征性的临床和影像学表现，因此在没有组织病理学和免疫组织化学检查的情况下很难做出正确诊断。本报告描述了一例30岁男性下颌骨嗜酸性肉芽肿病例，该患者因拔牙创口未愈合前来就诊，临床诊断为慢性化脓性骨髓炎。仅在进行组织病理学和免疫组织化学评估后才做出嗜酸性肉芽肿的最终诊断。
