Tian Lijie, Ji Xianglu, Chen Ting, Qi Feng, Tian Furong, Yao Qiang, Tian Feng
Department of Hand and Foot Surgery, Shengjing Hospital of China Medical University, Shenyang, 110004, People's Republic of China.
Department of Hand and Foot Surgery, Shenwei Hospital Shenyang, Shenyang, 110000, People's Republic of China.
Cell Tissue Bank. 2019 Mar;20(1):109-115. doi: 10.1007/s10561-018-09745-4. Epub 2019 Jan 12.
To evaluate the clinical outcome of deep hypothermic preservation of autologous skin in the treatment of large-area skin avulsion. Medium or full thickness-skin slices were harvested from large avulsion flaps between July and November 2017. They were stored in liquid nitrogen by vitrification. After the patient's condition became stable and the growth of the wound granulation tissue was satisfactory, the frozen skin slices were reheated quickly and replanted to the wound. Autologous skin that had been kept by deep cryopreservation had a high survival rate when grafted. It did not create new trauma or bring additional pain to patients. Yet it could shorten the course of treatment and reduce the medical cost for patients. It is an effective and economical way to treat large-area skin avulsion.
评估自体皮肤深低温保存治疗大面积皮肤撕脱伤的临床疗效。于2017年7月至11月从大面积撕脱皮瓣上取下中厚或全厚皮片，采用玻璃化法液氮保存。待患者病情稳定、创面肉芽组织生长良好后，将冻存皮片快速复温后回植于创面。经深低温保存的自体皮肤移植时成活率高，未给患者造成新的创伤及额外痛苦，且能缩短患者治疗疗程，降低医疗费用，是治疗大面积皮肤撕脱伤的一种有效且经济的方法。
