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妇产科手术后膀胱阴道瘘(VVF)的临床相关性及治疗结果

Clinical relevance and treatment outcomes of vesicovaginal fistula (VVF) after obstetric and gynecologic surgery.

作者信息

Lo Tsia-Shu, Chua Sandy, Wijaya Tomy, Kao Chuan Chi, Uy-Patrimonio Ma Clarissa

机构信息

Department of Obstetrics and Gynaecology, Chang Gung Memorial Hospital, Keelung Medical Center, Keelung, Taiwan, Republic of China; Division of Urogynaecology, Department of Obstetrics and Gynaecology, Chang Gung Memorial Hospital, Linkou Medical Center, Taoyuan, Taiwan, Republic of China; Chang Gung University, School of Medicine, Taoyuan, Taiwan, Republic of China.

Fellow, Division of Urogynaecology, Department of Obstetrics and Gynaecology, Chang Gung Memorial Hospital, Linkou Medical Center, Taoyuan, Taiwan, Republic of China; Department of Obstetrics and Gynecology, Cebu Velez General Hospital, Cebu City, Philippines.

出版信息

Taiwan J Obstet Gynecol. 2019 Jan;58(1):111-116. doi: 10.1016/j.tjog.2018.11.021.

Abstract

OBJECTIVE

Vesicovaginal fistulas (VVF) are consequences from obstetric and gynecologic surgery. Treatment approach from either abdominal or vaginal route have its own pros and cons. The study aims to present the anatomical, clinical and lower urinary tract symptom outcomes of women with VVF.

MATERIALS AND METHODS

A retrospective case series conducted patients with VVF. Data regarding pre-operative evaluation, surgical treatment, and post-operative follow-ups were collected. Surgical approach depended on the cause, type, number, size, location, and time of onset of the fistula. Post-operatively, foley catheter was maintained for at least 1 week with cystoscopy performed prior to removal. Follow-up evaluation included cystoscopy, bladder diary, UDI-6 and IIQ-7 questionnaires and multi-channel urodynamic study.

RESULTS

Of the 15 patients that were evaluated, 1 had spontaneous closure, 8 were repaired vaginally and 6 abdominally. Patients repaired vaginally were significantly noted to have a mean age of 50.3 ± 7.1 years with VVFs located adjacent the supra-trigone area having a mean distance of 1.7 ± 0.5 cm from the ureteric orifice. Its operative time and hospital stay were significantly shorter. In contrast, abdominally repaired patients had mean age of 38.0 ± 8.2 years and VVFs with mean distance of 0.4 ± 0.4 cm from the ureteric orifice. Post-operatively, 2 cases (14.2%, 2/14) of VVF recurrence and de novo urodynamic stress incontinence (USI) (25%, 2/8) were noted after vaginal repair and 3 cases (50%, 3/6) of concurrent ureteric injury and overactive bladder after abdominal repair.

CONCLUSION

Treatment outcomes for vaginal and abdominal repair yielded good results. Though the vaginal route had higher incidence of recurrence and de novo USI, its less invasiveness, faster recovery period, and no association with post-op overactive bladder made it more preferable than the abdominal approach.

摘要

目的

膀胱阴道瘘(VVF)是妇产科手术的并发症。经腹或经阴道途径的治疗方法各有优缺点。本研究旨在呈现膀胱阴道瘘女性患者的解剖学、临床及下尿路症状结果。

材料与方法

对膀胱阴道瘘患者进行回顾性病例系列研究。收集术前评估、手术治疗及术后随访的数据。手术方式取决于瘘管的病因、类型、数量、大小、位置及发病时间。术后,保留 Foley 导尿管至少 1 周,拔除前进行膀胱镜检查。随访评估包括膀胱镜检查、膀胱日记、UDI - 6 和 IIQ - 7 问卷以及多通道尿动力学研究。

结果

在评估的 15 例患者中,1 例自发闭合,8 例经阴道修复,6 例经腹修复。经阴道修复的患者平均年龄为 50.3±7.1 岁,膀胱阴道瘘位于膀胱三角区上方附近,距输尿管口平均距离为 1.7±0.5cm。其手术时间和住院时间明显较短。相比之下,经腹修复的患者平均年龄为 38.0±8.2 岁,膀胱阴道瘘距输尿管口平均距离为 0.4±0.4cm。术后,经阴道修复后有 2 例(14.2%,2/14)膀胱阴道瘘复发和新发尿动力学压力性尿失禁(USI)(25%,2/8),经腹修复后有 3 例(50%,3/6)并发输尿管损伤和膀胱过度活动症。

结论

经阴道和经腹修复的治疗效果良好。虽然经阴道途径复发和新发 USI 的发生率较高,但其侵入性较小、恢复期较短且与术后膀胱过度活动症无关,使其比经腹途径更可取。

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