Kervyn A, Le Guern A, Gillard M, Bataille M, Modiano P
Service de dermatologie, université catholique Lille, hôpital Saint-Vincent de Paul, boulevard de Belfort - BP 387, 59020 Lille cedex, France.
Service de dermatologie, université catholique Lille, hôpital Saint-Vincent de Paul, boulevard de Belfort - BP 387, 59020 Lille cedex, France.
Ann Dermatol Venereol. 2019 Feb;146(2):131-134. doi: 10.1016/j.annder.2018.11.004. Epub 2019 Jan 9.
Tularaemia is a zoonotic disease caused by inoculation with the Gram-negative coccobacillus Francisella tularensis. It was first described in the United States in 1911 and is a rare disease with an annual reported incidence in France between 2002 and 2012 of 0.07 cases per 100,000 habitants. Reporting of the disease in humans has been mandatory in France since 2003.
Herein we report a case of tularaemia following a tick bite in a patient in the north of France.
Tularaemia is a rare form of zoonosis that should be sought in the event of unexplained adenitis. Clinical presentations vary, and in certain cases only dermatological signs are manifest. Diagnosis is confirmed by bacterial serology. Rapid initiation of suitable antibiotics produces a favourable and benign outcome in most cases. However, the offending organism, which is potentially lethal, is classed as a potential bioterrorism agent.
兔热病是一种人畜共患病，由革兰氏阴性球杆菌土拉弗朗西斯菌接种引起。该病于1911年在美国首次被描述，是一种罕见疾病，2002年至2012年期间法国每年报告的发病率为每10万居民0.07例。自2003年起，法国规定必须报告人类感染该疾病的情况。
在此我们报告法国北部一名患者被蜱叮咬后患上兔热病的病例。
兔热病是一种罕见的人畜共患病形式，在出现不明原因腺炎时应考虑该病。临床表现各异，在某些情况下仅表现为皮肤症状。通过细菌血清学确诊。在大多数情况下，迅速开始使用合适的抗生素可产生良好且良性的结果。然而，这种具有潜在致命性的致病生物被列为潜在的生物恐怖主义制剂。
