Department of Internal Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Department of Internal Medicine, University of Medicine and Pharmacy at Ho Chi Minh City, Ho Chi Minh City, Vietnam.
Int J Infect Dis. 2019 Mar;80:80-83. doi: 10.1016/j.ijid.2019.01.001. Epub 2019 Jan 9.
Endobronchial tuberculosis (EBTB) is a challenging diagnosis because of its varied clinical and radiological manifestations. Hilar asymmetry on chest radiograph (CXR) may be found in patient with EBTB but is often overlooked, which may lead to delayed diagnosis.
We present five cases with EBTB. Clinicians failed to identify unilateral hilar abnormalities on CXR, and these patients were treated initially for pharyngitis, bronchitis, or pneumonia with no improvement. Subsequently, they visited the pulmonary clinic and bronchoscopy revealed endobronchial lesions and microbial/histopathological evidence of tuberculous infection consistent with EBTB. Anti-tuberculosis therapy resulted in complete clinical resolution in four of the five patients; one patient had persistent bronchial stenosis.
Hilar asymmetry on CXR may occur with EBTB and may suggest this diagnosis in the appropriate clinical setting. Bronchoscopy has an important role in establishing the final diagnosis.
支气管内膜结核(EBTB)的临床表现和影像学表现多样,诊断具有挑战性。胸部 X 线摄影(CXR)可能会发现 EBTB 患者的肺门不对称,但常被忽视,这可能导致诊断延迟。
我们报告了 5 例 EBTB 患者。临床医生未能在 CXR 上识别单侧肺门异常,这些患者最初因咽炎、支气管炎或肺炎接受治疗,但没有改善。随后,他们到呼吸科就诊,支气管镜检查显示支气管内病变,微生物/组织病理学证据表明存在结核感染,符合 EBTB 诊断。抗结核治疗使 5 例患者中的 4 例完全临床缓解;1 例患者持续存在支气管狭窄。
EBTB 可出现肺门不对称,在适当的临床环境下可能提示该诊断。支气管镜检查在明确最终诊断方面具有重要作用。