Département de Médecine Générale, Université de Lorraine, Vandoeuvre-les-Nancy, France.
Département de Médecine Générale, Université de Lorraine, Vandoeuvre-les-Nancy, France; INSERM, Centre d'Investigations Cliniques Plurithématique 1433, UMR 1116, Université de Lorraine and CHU de Nancy, Vandoeuvre-lès-Nancy, France.
Psychiatry Res. 2019 Mar;273:30-36. doi: 10.1016/j.psychres.2018.12.154. Epub 2019 Jan 5.
A prospective study often receives a low participation rate that may alter the results quality. This study assessed the participation bias for a confidential non-anonymous adolescent survey among 1559 middle-school adolescents from north-eastern France (mean age 13.5 ± 1.3). They completed an anonymous questionnaire gathering demographic/socioeconomic features as well as school, behavior and health-related difficulties, and adolescent's assent to participate with perceived parents' consent (APC) if they were contacted for a confidential non-anonymous survey at home. Such a survey received an APC of 60%. The logistic model including all socioeconomic factors and school, behavior and health-related difficulties showed that the adolescents with APC were less often male (adjusted odds ratio = 0.77, p = 0.014), non-European immigrant (0.48, p = 0.016), living with a single parent (0.72, p = 0.046), in manual-worker families (0.69, p = 0.007), had less often low parents' education (0.70, p = 0.002), body-mass-index measurement refusal (0.60, p = 0.010), no regular physical/sports activity (0.70, p = 0.035), poor social relationships (0.73, p = 0.046) and poor living environment (0.63, p = 0.007). The percentage of subjects with APC steadily decreased with the number of these criteria: from 74% for 0 criterion to 19% for 6-8 criteria. Because of these possible strong participation biases the construction of adolescent cohorts and the results interpretation should be made with prudence.
一项前瞻性研究通常参与率较低，这可能会改变研究结果的质量。本研究评估了法国东北部地区的 1559 名中学生参与一项保密、非匿名青少年调查的偏倚程度（平均年龄 13.5±1.3 岁）。他们完成了一份匿名问卷，收集了人口统计学/社会经济特征以及学校、行为和健康相关困难，以及青少年在被联系进行保密、非匿名家庭调查时对参与的同意（APC），如果他们同意，则视为父母同意（APC）。这种调查收到了 60%的 APC。包括所有社会经济因素以及学校、行为和健康相关困难的逻辑模型表明，具有 APC 的青少年中，男性（调整后的优势比 = 0.77，p = 0.014）、非欧洲移民（0.48，p = 0.016）、与单亲父母同住（0.72，p = 0.046）、父母从事体力劳动（0.69，p = 0.007）、父母受教育程度低（0.70，p = 0.002）、拒绝进行体重指数测量（0.60，p = 0.010）、无规律的体育活动（0.70，p = 0.035）、社会关系较差（0.73，p = 0.046）和生活环境较差（0.63，p = 0.007）的青少年比例较低。具有 APC 的受试者比例随着这些标准数量的增加而稳步下降：从 0 个标准的 74%下降到 6-8 个标准的 19%。由于这些可能存在的强烈参与偏差，应该谨慎构建青少年队列并解释研究结果。
