新型生物生产系统用于化学品和燃料：需求与新发展。
New bioproduction systems for chemicals and fuels: Needs and new development.
机构信息
Beijing Advanced Innovation Center for Soft Matter Science and Engineering, Beijing University of Chemical Technology, North Third Ring Road 15, Chaoyang District, 100029 Beijing, China; Institute of Bioprocess and Biosystems Engineering, Hamburg University of Technology, Denickestrasse 15, D-21073 Hamburg, Germany.
出版信息
Biotechnol Adv. 2019 Jul-Aug;37(4):508-518. doi: 10.1016/j.biotechadv.2019.01.003. Epub 2019 Jan 11.
Currently used bioproduction systems for chemicals and fuels are primarily based on sugar-containing substrates. They have inherent limitations regarding substrate sustainability and affordability, product spectrum and yield, and costs for up- and downstream processing. To overcome some of these major burdens new bioproduction strategies and systems are being developed, including biorefinery, electro-biotechnology (use of electricity for biosynthesis) and C1 bioeconomy using synthetic biological systems based on C1 carbon feedstocks such as CO, CO, methane, methanol and formic acid. In this article, the promises, development trends and challenges of these new bioproduction systems and concepts are briefly summarized and discussed.
目前用于化学品和燃料的生物生产系统主要基于含糖类的底物。它们在底物可持续性和可负担性、产品谱和产率以及上下游加工成本方面存在固有局限性。为了克服其中的一些主要负担，正在开发新的生物生产策略和系统，包括生物炼制、电生物技术（使用电力进行生物合成）和基于 C1 碳原料（如 CO、CO2、甲烷、甲醇和甲酸）的合成生物学系统的 C1 生物经济。本文简要总结和讨论了这些新的生物生产系统和概念的前景、发展趋势和挑战。
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