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儿童中耳炎分离株肺炎链球菌EF3030的基因组序列草图，该菌株形成的生物膜与生物膜极为相似。

Draft Genome Sequence of Pediatric Otitis Media Isolate Streptococcus pneumoniae Strain EF3030, Which Forms Biofilms That Closely Mimic Biofilms.

作者信息

Scott Edgar J, Luke-Marshall Nicole R, Campagnari Anthony A, Dyer David W

机构信息

Department of Microbiology and Immunology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA.

Department of Microbiology and Immunology, State University of New York at Buffalo, Buffalo, New York, USA.

出版信息

Microbiol Resour Announc. 2019 Jan 10;8(2). doi: 10.1128/MRA.01114-18. eCollection 2019 Jan.

DOI:10.1128/MRA.01114-18
PMID:30643873
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6328646/
Abstract

Here, we report the draft genome sequence of Streptococcus pneumoniae EF3030, a pediatric otitis media isolate active in biofilm assays of epithelial colonization. The final draft assembly included 2,209,198 bp; the annotation predicted 2,120 coding DNA sequences (CDSs), 4 complete rRNA operons, 58 tRNAs, 3 noncoding RNAs (ncRNAs), and 199 pseudogenes.

摘要

在此，我们报告肺炎链球菌EF3030的基因组序列草图，该菌株分离自一名患有中耳炎的儿童，在生物膜上皮定植试验中具有活性。最终的草图组装包含2,209,198个碱基对；注释预测有2,120个编码DNA序列（CDS）、4个完整的rRNA操纵子、58个tRNA、3个非编码RNA（ncRNA）和199个假基因。

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