Komov V P, Spasenkova O M, Strelkova M A
Vopr Med Khim. 1988 Sep-Oct;34(5):72-6.
Proteolytic activity was studied in bronchoalveolar lavage in dynamics of rat bronchial anaphylaxis; in the disease alkaline proteinases were activated. Physico-chemical properties of an alkaline proteinase, isolated from the rat lavage, were studied. Quantitative metabolic patterns of the enzyme metabolism, involving the rates of its synthesis and decomposition as well as a period of the newly synthesized protein functioning, were evaluated. Under conditions of bronchial anaphylaxis the parameters of the proteinase turnover were altered in bronchopulmonary system.
在大鼠支气管过敏反应的动态过程中，对支气管肺泡灌洗中的蛋白水解活性进行了研究；在该疾病中，碱性蛋白酶被激活。对从大鼠灌洗液中分离出的一种碱性蛋白酶的物理化学性质进行了研究。评估了酶代谢的定量代谢模式，包括其合成和分解速率以及新合成蛋白质发挥作用的时期。在支气管过敏反应的条件下，支气管肺系统中蛋白酶周转的参数发生了改变。
