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内镜下真空治疗(EVT)用于减重手术后早期膈下渗漏——单机构连续6例病例的结果

Endoscopic vacuum therapy (EVT) for early infradiaphragmal leakage after bariatric surgery-outcomes of six consecutive cases in a single institution.

作者信息

Morell Bernhard, Murray Fritz, Vetter Diana, Bueter Marco, Gubler Christoph

机构信息

Division of Gastroenterology and Hepatology, University Hospital Zurich, Raemistrasse 100, 8091, Zurich, Switzerland.

Division of Surgery and Transplantation, University Hospital Zurich, Raemistrasse 100, 8091, Zurich, Switzerland.

出版信息

Langenbecks Arch Surg. 2019 Feb;404(1):115-121. doi: 10.1007/s00423-019-01750-9. Epub 2019 Jan 15.

Abstract

PURPOSE

Anastomotic leakages or staple line defects after Roux-en-Y gastric bypass (RYGB) and primary laparoscopic sleeve gastrectomy (LSG), respectively, with consecutive bariatric revisional surgery are associated with relevant morbidity and mortality rates. Endoscopic vacuum therapy (EVT) with or without stent-over-sponge (SOS) has been shown to be a promising therapy in foregut wall defects of various etiologies and may therefore be applied in the treatment of postbariatric leaks.

METHODS

We report the results of six consecutive patients treated with EVT (83% in combination with SOS) for early postoperative leakages in close proximity to the esophagogastric junction (EGJ) after LSG (n = 2) and RYGB (n = 4) from May 2016 to May2018.

RESULTS

All patients (2/6 male, median age 51 years, median BMI 44.2 kg/m) were treated successfully without further signs of persisting leakage at the last gastroscopy. The lesions' size ranged from 0.5 cm to 9 cm, and the leaks were connected to large (max. 225 cm) abscess cavities in 80% of the cases. Median duration of treatment (= EVT in situ) was 23.5 days (range, 7-89). The number of endoscopic interventions ranged from 1 to 24 (median, n = 7), with a median duration between vacuum sponge replacements of 4 days.

CONCLUSION

EVT is an effective and safe treatment for staple line defects or anastomotic leakage after bariatric surgeries and can therefore be adopted for the treatment of midgut wall defects. Further studies with a greater number of patients comparing surgical drainage alone or in combination with EVT versus EVT alone are needed.

摘要

目的

在接受连续减肥修正手术的患者中,Roux-en-Y胃旁路术(RYGB)和初次腹腔镜袖状胃切除术(LSG)后分别出现的吻合口漏或吻合钉线缺损与相关的发病率和死亡率有关。内镜下真空治疗(EVT)联合或不联合海绵上支架(SOS)已被证明是治疗各种病因的前肠壁缺损的一种有前景的治疗方法,因此可应用于减肥术后漏的治疗。

方法

我们报告了2016年5月至2018年5月期间,连续6例接受EVT(83%联合SOS)治疗的患者,这些患者在LSG(n = 2)和RYGB(n = 4)后,在食管胃交界(EGJ)附近出现早期术后漏。

结果

所有患者(2/6为男性,中位年龄51岁,中位BMI 44.2kg/m²)均成功接受治疗,最后一次胃镜检查时无持续漏的进一步迹象。病变大小从0.5cm到9cm不等,80%的病例中漏与大的(最大225cm)脓肿腔相连。中位治疗持续时间(=原位EVT)为23.5天(范围7 - 89天)。内镜干预次数从1次到24次不等(中位值,n = 7),真空海绵更换之间的中位持续时间为4天。

结论

EVT是减肥手术后吻合钉线缺损或吻合口漏的一种有效且安全的治疗方法,因此可用于治疗中肠壁缺损。需要进行更多患者的进一步研究,比较单独手术引流或联合EVT与单独EVT的效果。

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