Prescrire Int. 2016 Oct;25(175):233.
In an unblinded trial in 452 patients with persistent, recurrent or metastatic cervical cancer, adding bevacizumab to other cytotoxic drugs prolonged median survival by 4 months, but adverse effects were often severe and sometimes fatal. Tailored symptomatic care is also a valid option.
在一项针对452例持续性、复发性或转移性宫颈癌患者的非盲法试验中,在其他细胞毒性药物基础上加用贝伐单抗可使中位生存期延长4个月,但不良反应往往很严重,有时甚至致命。针对性的对症治疗也是一种有效的选择。