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[脂肪酸的反式异构体:健康风险及减少摄入量的方法]

[Trans isomers of fatty acids: health risks and ways to reduce consumption].

作者信息

Bessonov V V, Zaytseva L V

机构信息

Federal Research Centre of Nutrition, Biotechnology and Food Safety, Moscow.

Union of Food Producers of the Customs Union, Moscow.

出版信息

Vopr Pitan. 2016;85(3):6-17. doi: 10.24411/0042-8833-2016-00030. Epub 2016 Jun 23.

DOI:10.24411/0042-8833-2016-00030
PMID:30645898
Abstract

The review presents the analysis of data to assess the health effects of various trans fatty acids. The analysis of the scientific literature indicates that a biological effect is dependent on the type of trans fatty acid. Based on the presented analysis it is shown that the introduction of hygienic rationing content of trans fatty acids (TFAs) should be differentiated according to which of TFAs should be considered to be hazardous to humans. The review presents data justifying the exclusion of some TFAs (rumenic and vaccenic acid) from the total combined content of trans fatty acids while limiting their consumption. These acids are proven to be attributed to functional food factors preventing the risk of various diseases. Rumenic acid and 10-trans-12-cis-octadecadienoic acid may also be used in drug therapy. Due to the positive biological activity of the two isomers of octadecadienoic acid with conjugated bonds, TFAs with conjugated bonds were excluded from the definition of TFAs adopted the Codex Alimentarius Commission and used in official documents of a number of countries. Overview material presented in the article confirms the thesis that the ban on the content of TFAs, or limitation on the legislative level, is a more effective method compared to mandatory labeling. Conducting a valuation of TFAs contents of certain substances is justified from the point of view of analytical chemistry, since the practice of monitoring implemented a method to determine the individual ENG 28 one, two and three double bonds. The article also discussed the various methods for reducing the content of TFAs in food products.

摘要

该综述对数据进行了分析,以评估各种反式脂肪酸对健康的影响。科学文献分析表明,生物效应取决于反式脂肪酸的类型。基于所呈现的分析结果显示,应根据哪些反式脂肪酸被认为对人类有害,来区分引入反式脂肪酸(TFAs)的卫生定量标准。该综述提供的数据证明,在限制某些反式脂肪酸(瘤胃酸和vaccenic酸)的消费量时,应将其从反式脂肪酸的总含量中排除。这些酸被证明属于功能性食品因子,可预防各种疾病。瘤胃酸和10-反式-12-顺式-十八碳二烯酸也可用于药物治疗。由于具有共轭双键的十八碳二烯酸的两种异构体具有积极的生物活性,具有共轭双键的反式脂肪酸被排除在食品法典委员会采用并在一些国家的官方文件中使用的反式脂肪酸定义之外。文章中呈现的综述材料证实了这样一个论点,即与强制标签相比,禁止反式脂肪酸含量或在立法层面进行限制是一种更有效的方法。从分析化学的角度来看,对某些物质的反式脂肪酸含量进行评估是合理的,因为监测实践采用了一种方法来确定单个的、具有一个、两个和三个双键的反式脂肪酸。文章还讨论了降低食品中反式脂肪酸含量的各种方法。

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