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根据欧洲心脏手术风险评估系统(EuroSCORE)评估急性冠状动脉综合征患者及冠状动脉搭桥术前不同胆囊状况患者的心脏外科手术干预风险。

Estimation of cardiosurgical intervention risk according to EuroSCORE in patients with acute coronary syndrome and different gallbladder conditions before coronary artery bypass grafting.

作者信息

Strilchuk Larysa, Besh Dmytro

机构信息

Department of Therapy and Medical Diagnostics, Lviv National Medical University named after Danylo Halytsky, Lviv, Ukraine.

Department of Family Medicine, Lviv National Medical University named after Danylo Halytsky, Lviv, Ukraine.

出版信息

Kardiochir Torakochirurgia Pol. 2018 Dec;15(4):238-240. doi: 10.5114/kitp.2018.80920. Epub 2018 Dec 31.

DOI:10.5114/kitp.2018.80920
PMID:30647747
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6329887/
Abstract

INTRODUCTION

Estimation of cardiosurgical intervention risk according to EuroSCORE is an important aspect of cardiosurgery. EuroSCORE allows prediction of the probability of a post-operational fatal outcome.

AIM

To estimate the influence of gallbladder condition on the prognosis after coronary artery bypass grafting (CABG) and and the interactions between metabolic background and cardiosurgical intervention risk.

MATERIAL AND METHODS

We investigated data of 98 patients with unstable angina pectoris or acute myocardial infarction before planned CABG. These patients were divided into the following groups according to their gallbladder condition: intact bladder; bile sludge or cholesterosis; bent gallbladder body; gallbladder neck deformations or cholecystitis; cholelithiasis; history of cholecystectomy.

RESULTS

The mean cardiosurgical intervention risk score according to the EuroSCORE system in our patients was 6.03 ±0.62%. It was significantly higher in patients with low serum bilirubin levels. There were direct correlations between the risk score result and presence of left ventricular dilatation ( = 0.31, < 0.05) and fasting glucose level ( = 0.82, < 0.01), as well as with means of other parameters, i.e., left atrial dimension, right ventricular size, grade of stenosis of anterior interventricular branch of left coronary artery, serum levels of total cholesterol, β-lipoproteins, bilirubin and potassium.

CONCLUSIONS

These correlations suggest that the EuroSCORE results estimated before surgery may be used as a simple informative prognostic criterion of intra-operational cardiac mortality and also as a marker of structural and functional heart condition and metabolic background. However, these correlations were different in patients with different gallbladder conditions.

摘要

引言

根据欧洲心脏手术风险评估系统(EuroSCORE)评估心脏外科手术干预风险是心脏外科的一个重要方面。EuroSCORE可预测术后致命结局的概率。

目的

评估胆囊状况对冠状动脉旁路移植术(CABG)后预后的影响以及代谢背景与心脏外科手术干预风险之间的相互作用。

材料与方法

我们调查了98例计划进行CABG的不稳定型心绞痛或急性心肌梗死患者的数据。这些患者根据胆囊状况分为以下几组:胆囊完好;胆汁淤积或胆固醇沉着症;胆囊体弯曲;胆囊颈部变形或胆囊炎;胆结石;胆囊切除术史。

结果

根据EuroSCORE系统,我们患者的平均心脏外科手术干预风险评分为6.03±0.62%。血清胆红素水平低的患者该评分显著更高。风险评分结果与左心室扩张(r = 0.31,P < 0.05)、空腹血糖水平(r = 0.82,P < 0.01)以及其他参数的均值,即左心房内径、右心室大小、左冠状动脉前室间支狭窄程度、总胆固醇、β-脂蛋白、胆红素和钾的血清水平之间存在直接相关性。

结论

这些相关性表明,术前评估的EuroSCORE结果可作为术中心脏死亡率的简单信息性预后标准,也可作为心脏结构和功能状况以及代谢背景的标志物。然而,不同胆囊状况患者的这些相关性有所不同。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e3c/6329887/bb10c02b023f/KITP-15-80920-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e3c/6329887/bb10c02b023f/KITP-15-80920-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6e3c/6329887/bb10c02b023f/KITP-15-80920-g001.jpg

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