Battling quiescence for tumor eradication: too good to be true?
作者信息
McCarty Nami
机构信息
Nami McCarty: Brown Foundation Institute of Molecular Medicine for the Prevention of Human Diseases (IMM), University of Texas-Health Science Center at Houston, Houston, TX, USA.
出版信息
Oncotarget. 2018 Dec 18;9(99):37276-37277. doi: 10.18632/oncotarget.26452.
Abstract
摘要
相似文献
1
Battling quiescence for tumor eradication: too good to be true?对抗肿瘤休眠以实现根除：好得难以置信？
Oncotarget. 2018 Dec 18;9(99):37276-37277. doi: 10.18632/oncotarget.26452.
2
Autophagy mediates serum starvation-induced quiescence in nucleus pulposus stem cells by the regulation of P27.自噬通过调节 P27 介导血清饥饿诱导的髓核干细胞静止。
Stem Cell Res Ther. 2019 Apr 15;10(1):118. doi: 10.1186/s13287-019-1219-8.
3
Status of mTOR activity may phenotypically differentiate senescence and quiescence.mTOR 活性的状态可能表型上区分衰老和静止。
Mol Cells. 2012 Jun;33(6):597-604. doi: 10.1007/s10059-012-0042-1. Epub 2012 May 7.
4
In quiescence of fission yeast, autophagy and the proteasome collaborate for mitochondrial maintenance and longevity.在裂殖酵母的静止期，自噬和蛋白酶体协同作用以维持线粒体和延长寿命。
Autophagy. 2010 May;6(4):564-5. doi: 10.4161/auto.6.4.11948. Epub 2010 May 16.
5
Effect of cellular quiescence on the success of targeted CML therapy.细胞静止对靶向性慢性粒细胞白血病治疗成功的影响。
PLoS One. 2007 Oct 3;2(10):e990. doi: 10.1371/journal.pone.0000990.
6
Autophagy drives the conversion of developmental neural stem cells to the adult quiescent state.自噬促使发育中的神经干细胞向成体静息状态转化。
Nat Commun. 2023 Nov 24;14(1):7541. doi: 10.1038/s41467-023-43222-1.
7
Staying alive: metabolic adaptations to quiescence.存活下去：静止期的代谢适应。
Cell Cycle. 2012 May 1;11(9):1680-96. doi: 10.4161/cc.19879.
8
Autophagy Is Indispensable for the Self-Renewal and Quiescence of Ovarian Cancer Spheroid Cells with Stem Cell-Like Properties.自噬对于具有干细胞样特性的卵巢癌细胞球自我更新和静止是必不可少的。
Oxid Med Cell Longev. 2018 Sep 17;2018:7010472. doi: 10.1155/2018/7010472. eCollection 2018.
9
The Rim15-endosulfine-PP2ACdc55 signalling module regulates entry into gametogenesis and quiescence via distinct mechanisms in budding yeast.Rim15-内硫磷蛋白-PP2ACdc55信号模块通过芽殖酵母中不同的机制调控配子发生和静止期的进入。
PLoS Genet. 2014 Jun 26;10(6):e1004456. doi: 10.1371/journal.pgen.1004456. eCollection 2014 Jun.
10
TRIM Family Proteins: Roles in Autophagy, Immunity, and Carcinogenesis.TRIM 家族蛋白：在自噬、免疫和癌症发生中的作用。
Trends Biochem Sci. 2017 Apr;42(4):297-311. doi: 10.1016/j.tibs.2017.01.002. Epub 2017 Jan 22.
引用本文的文献
1
TRIM44 links the UPS to SQSTM1/p62-dependent aggrephagy and removing misfolded proteins.TRIM44 将 UPS 与 SQSTM1/p62 依赖性聚集体自噬连接起来，并清除错误折叠的蛋白质。
Autophagy. 2022 Apr;18(4):783-798. doi: 10.1080/15548627.2021.1956105. Epub 2021 Aug 12.
本文引用的文献
1
Osteoblast-Secreted Factors Mediate Dormancy of Metastatic Prostate Cancer in the Bone via Activation of the TGFβRIII-p38MAPK-pS249/T252RB Pathway.成骨细胞分泌因子通过激活 TGFβRIII-p38MAPK-pS249/T252RB 通路介转移前列腺癌在骨中的休眠。
Cancer Res. 2018 Jun 1;78(11):2911-2924. doi: 10.1158/0008-5472.CAN-17-1051. Epub 2018 Mar 7.
2
Packaging and transfer of mitochondrial DNA via exosomes regulate escape from dormancy in hormonal therapy-resistant breast cancer.外泌体介导的线粒体 DNA 包装和转移调控激素治疗抵抗性乳腺癌休眠逃逸。
Proc Natl Acad Sci U S A. 2017 Oct 24;114(43):E9066-E9075. doi: 10.1073/pnas.1704862114. Epub 2017 Oct 11.
3
NR2F1 controls tumour cell dormancy via SOX9- and RARβ-driven quiescence programmes.NR2F1通过SOX9和RARβ驱动的静止程序控制肿瘤细胞休眠。
Nat Commun. 2015 Jan 30;6:6170. doi: 10.1038/ncomms7170.
4
Ubiquitination in disease pathogenesis and treatment.泛素化在疾病发病机制和治疗中的作用。
Nat Med. 2014 Nov;20(11):1242-53. doi: 10.1038/nm.3739. Epub 2014 Nov 6.
5
TRIM proteins regulate autophagy and can target autophagic substrates by direct recognition.TRIM蛋白调节自噬，并可通过直接识别靶向自噬底物。
Dev Cell. 2014 Aug 25;30(4):394-409. doi: 10.1016/j.devcel.2014.06.013. Epub 2014 Aug 7.
6
Osteoblastic niche supports the growth of quiescent multiple myeloma cells.成骨细胞龛支持静止多发性骨髓瘤细胞的生长。
Blood. 2014 Apr 3;123(14):2204-8. doi: 10.1182/blood-2013-07-517136. Epub 2014 Jan 14.
7
A novel small molecule inhibitor of deubiquitylating enzyme USP14 and UCHL5 induces apoptosis in multiple myeloma and overcomes bortezomib resistance.一种新型小分子去泛素化酶 USP14 和UCHL5 的抑制剂诱导多发性骨髓瘤细胞凋亡并克服硼替佐米耐药。
Blood. 2014 Jan 30;123(5):706-16. doi: 10.1182/blood-2013-05-500033. Epub 2013 Dec 6.
8
A SNP microarray and FISH-based procedure to detect allelic imbalances in multiple myeloma: an integrated genomics approach reveals a wide gene dosage effect.一种用于检测多发性骨髓瘤中等位基因失衡的单核苷酸多态性微阵列和基于荧光原位杂交的方法：一种综合基因组学方法揭示了广泛的基因剂量效应。
Genes Chromosomes Cancer. 2009 Jul;48(7):603-14. doi: 10.1002/gcc.20668.
9
Leukemia and hematopoietic stem cells: balancing proliferation and quiescence.白血病与造血干细胞：平衡增殖与静止
Cell Cycle. 2008 Mar 1;7(5):586-91. doi: 10.4161/cc.7.5.5549. Epub 2008 Jan 1.
10
Gene-expression signature of benign monoclonal gammopathy evident in multiple myeloma is linked to good prognosis.多发性骨髓瘤中明显的良性单克隆丙种球蛋白病的基因表达特征与良好预后相关。
Blood. 2007 Feb 15;109(4):1692-700. doi: 10.1182/blood-2006-07-037077. Epub 2006 Oct 5.
Zotero 插件