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一名小叶性乳腺癌转移至骨髓患者的骨髓痨性贫血

Myelophthisic Anemia in a Patient with Lobular Breast Carcinoma Metastasized to the Bone Marrow.

作者信息

Khan Muhammad H, Patel Abdurraoof, Patel Purav, Patel Poras, Guevara Elizabeth

机构信息

Internal Medicine, The Brooklyn Hospital Center, Brooklyn, USA.

Hematology / Oncology, The Brooklyn Hospital Center, Brooklyn, USA.

出版信息

Cureus. 2018 Nov 4;10(11):e3541. doi: 10.7759/cureus.3541.

DOI:10.7759/cureus.3541
PMID:30648074
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6324862/
Abstract

Breast tumors have a predilection for metastasizing to the bone leading to cells being displaced by the cancer cells subsequently producing immature leukocytes and erythrocytes in the peripheral blood. We present a case of a 57-year-old female who was found to have myelophthisic anemia secondary to stage four lobular breast carcinoma metastasized to the bone marrow after being misdiagnosed as having thrombotic thrombocytopenia purpura. Diagnosis of myelophthisic anemia requires a thorough workup and treatment is based upon secondary management of the malignancy.

摘要

乳腺肿瘤易转移至骨骼，导致细胞被癌细胞取代，随后外周血中产生未成熟的白细胞和红细胞。我们报告一例57岁女性，她在被误诊为血栓性血小板减少性紫癜后，被发现患有继发于四期小叶乳腺癌骨髓转移的骨髓痨性贫血。骨髓痨性贫血的诊断需要全面检查，治疗基于对恶性肿瘤的二级管理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2967/6324862/28ba8bc689dd/cureus-0010-00000003541-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2967/6324862/8f57ea44fe3c/cureus-0010-00000003541-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2967/6324862/6d3b60d46206/cureus-0010-00000003541-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2967/6324862/28ba8bc689dd/cureus-0010-00000003541-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2967/6324862/8f57ea44fe3c/cureus-0010-00000003541-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2967/6324862/6d3b60d46206/cureus-0010-00000003541-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2967/6324862/28ba8bc689dd/cureus-0010-00000003541-i03.jpg

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本文引用的文献

1
Breast cancer statistics, 2017, racial disparity in mortality by state.乳腺癌统计数据，2017 年，按州划分的死亡率种族差异。
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