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胃异位胰腺的急诊表现

Emergency Presentation of Gastric Ectopic Pancreas.

作者信息

Calcagno Pietro, Lotti Marco, Campanati Luca, Greco Salvatore, Trezzi Rosangela, Assolari Andrea, Vaterlini Elisa, Bertani Cristina, Allievi Niccolò, Giulii Capponi Michela

机构信息

Surgery, Papa Giovanni Xxiii Hospital, Bergamo, ITA.

Internal Medicine, Papa Giovanni Xxiii Hospital, Bergamo, ITA.

出版信息

Cureus. 2018 Nov 8;10(11):e3565. doi: 10.7759/cureus.3565.

Abstract

Ectopic pancreas is a rare embryological abnormality apparently not in association with others. Stomach and duodenum are the most common organs involved. Symptoms are nonspecific. Patients may complain of dyspepsia, abdominal pain or intestinal obstruction. Malignant evolution of ectopic pancreatic cells has been reported. Diagnosis can be very challenging due to the rarity of the disease and the absence of specific symptoms and radiological findings. We report two cases of young-adult men admitted to the emergency department due to acute upper gastro-intestinal and pancreatic symptoms. In both cases, during upper gastrointestinal endoscopy no mucosal vegetations were found. Endoscopic ultrasonography revealed gastric lesions originating from the muscularis propria, with a pattern suspected but not conclusive for malignancy. Fine needle aspiration was inconclusive in both cases. The patients underwent abdominal computed tomography, that showed gastric masses originating from the antrum and the lesser curvature of the stomach, with enlarged locoregional lymph nodes. According to the patients' symptoms, family history, radiological and cytological findings, the patients were scheduled for an explorative laparoscopy. In both cases, gastric ectopic pancreas was found. Clinical presentation of ectopic pancreas is heterogeneous and the diagnosis can be challenging, especially in an emergency setting. Endoscopic ultrasonography and fine needle aspiration can be useful for the diagnosis and clinical staging, but they can be unspecific. Diagnostic-therapeutic laparoscopy should be considered in symptomatic patients.

摘要

异位胰腺是一种罕见的胚胎学异常,显然与其他异常无关。胃和十二指肠是最常受累的器官。症状不具特异性。患者可能主诉消化不良、腹痛或肠梗阻。已有异位胰腺细胞发生恶性演变的报道。由于该病罕见且缺乏特异性症状和影像学表现,诊断可能极具挑战性。我们报告两例因急性上消化道和胰腺症状而入住急诊科的青年男性病例。在这两例病例中,上消化道内镜检查均未发现黏膜赘生物。内镜超声检查显示胃病变起源于固有肌层,有疑似但不能确诊为恶性的表现。两例病例的细针穿刺活检结果均不明确。患者接受了腹部计算机断层扫描,结果显示胃肿物起源于胃窦和胃小弯,局部淋巴结肿大。根据患者症状、家族史、影像学和细胞学检查结果,患者被安排进行探索性腹腔镜检查。两例病例均发现胃异位胰腺。异位胰腺的临床表现具有异质性,诊断可能具有挑战性,尤其是在急诊情况下。内镜超声检查和细针穿刺活检对诊断和临床分期可能有用,但可能不具特异性。对于有症状的患者,应考虑进行诊断性治疗性腹腔镜检查。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7684/6325026/ab5543f5fa8b/cureus-0010-00000003565-i01.jpg

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