Jain Akriti G, Tauseef Abubakar, Hasan Syed A, Jain Sanjay K, Wazir Mohammed, Majeed Umair
Internal Medicine, Florida Hospital, Orlando, USA.
Internal Medicine, Dow University of Health Sciences, Karachi, PAK.
Cureus. 2018 Nov 10;10(11):e3570. doi: 10.7759/cureus.3570.
Chronic lymphocytic leukemia (CLL) is characterized by excessive production of abnormal lymphocytes in the bone marrow. It usually presents as hepatosplenomegaly and lymphadenopathy along with constitutional symptoms of fever, tiredness, and weight loss. Pseudohyperkalemia may occur in patients with extreme leukocytosis. High serum and plasma potassium levels have been seen in pseudohyperkalemia. Whole blood potassium determination will usually help lead to a correct diagnosis. It is important to diagnose this condition early so that the patients are not inappropriately treated. We aim to highlight that hyperkalemia in CLL patients should only be treated if the patient is symptomatic or if the patient shows cardiac effects of hyperkalemia on electrocardiogram.
慢性淋巴细胞白血病(CLL)的特征是骨髓中异常淋巴细胞过度产生。它通常表现为肝脾肿大、淋巴结病以及发热、疲倦和体重减轻等全身症状。极度白细胞增多的患者可能会发生假性高钾血症。假性高钾血症患者可见血清和血浆钾水平升高。全血钾测定通常有助于做出正确诊断。早期诊断这种疾病很重要,这样患者就不会接受不恰当的治疗。我们旨在强调,只有当CLL患者出现症状或心电图显示高钾血症的心脏效应时,才应对其高钾血症进行治疗。