Vom Dorp F
Helios Klinikum Duisburg, Grunewaldstraße 96, 47053, Duisburg, Deutschland.
Urologe A. 2019 Jan;58(1):22-24. doi: 10.1007/s00120-018-0831-z.
Urothelial carcinoma of the upper urinary tract is a rare disease. Tumor biology is comparable to transitional cell carcinomas of the bladder. Local tumor control is much more difficult to achieve in the upper urinary tract than in the bladder. Radical nephroureterectomy is often performed due to carcinomas with low grade histology. Progression rates in these cases are rare; overtreatment has to be discussed. The current article uses the available published data to discuss whether local treatment is an option for tumors of the upper urinary tract. Summarizing the available data, it is indicated that if complete resectability is possible organ preservation is equivalent to radical nephroureterectomy independent of the T‑ and G‑category of the tumor.
上尿路尿路上皮癌是一种罕见疾病。肿瘤生物学特性与膀胱移行细胞癌相似。在上尿路实现局部肿瘤控制比在膀胱中困难得多。对于组织学分级低的癌，常进行根治性肾输尿管切除术。这些病例的进展率很低；必须讨论过度治疗的问题。本文利用已发表的现有数据来讨论局部治疗是否是上尿路肿瘤的一种选择。总结现有数据表明，如果能够完全切除，保留器官与根治性肾输尿管切除术等效，而与肿瘤的T和G分类无关。
