Migliorini Filippo, Eschweiler Jörg, Tingart Markus, Rath Björn
Department of Orthopaedics, RWTH Aachen University Clinic, Pauwelsstraße 30, 52074, Aachen, Germany.
Eur J Orthop Surg Traumatol. 2019 May;29(4):937-946. doi: 10.1007/s00590-019-02370-1. Epub 2019 Jan 16.
A meta-analysis comparing the outcomes of patients undergoing cruciate retaining (CR) versus posterior stabilized (PS) in primary total knee arthroplasty was performed. The outcomes of interest were the Knee Society Rating System, clinical (KSCS) and functional (KSFS) subscales, joint range of motion (ROM), surgical duration and further complications (anterior knee pain, instability and revision rate).
The search was conducted in July 2018, accessing the following databases: Cochrane Systematic Reviews, Scopus, PubMed, EMBASE, CINAHL, AMED and Google Scholar. We included only clinical trials level of evidence I and II. During the statistical analysis, we excluded all the studies that affect negatively the I test, in order to achieve more reliable results. For the methodological quality assessment we referred to the PEDro score. The risk of publication's bias was evaluated by the funnel plots across all the comparisons.
The PEDro score reported a good methodological quality assessment. The funnel plot detected a very low risk of publication's bias. We included in this study 36 articles, counting a total of 4052 patients and 4884 procedures. The mean follow-up term for both groups was 3.39 years. The ROM resulted in an overall estimate effect of 2.18° in favor of the PS group. The overall WOMAC showed a result in favor of the PS group. The overall estimate effect of the KSCS was 0.02% higher in the CR group. The KSFS showed an overall estimate effect of 2.09% in favor of the PS group. Concerning the surgical duration, the estimate effect resulted in 6.87 min shorter in the CR group. No differences were reported across the two groups regarding anterior knee pain, knee joint instability or revision rate.
Both the prosthetic implants provided to be a safety and feasible solution to treat end-stage knee joint degeneration. The PS implants reported improvements in the knee range of motion and a prolongation of the surgical time. No clinically relevant dissimilarities concerning the analyzed scores were evidenced. No statistically significant relevant differences in complications were detected.
进行一项荟萃分析,比较初次全膝关节置换术中采用保留交叉韧带(CR)与后稳定型(PS)假体的患者的手术效果。关注的结果指标包括膝关节协会评分系统、临床(KSCS)和功能(KSFS)子量表、关节活动范围(ROM)、手术时长以及进一步的并发症(膝前疼痛、不稳定和翻修率)。
于2018年7月进行检索,检索以下数据库:Cochrane系统评价、Scopus、PubMed、EMBASE、CINAHL、AMED和谷歌学术。我们仅纳入证据等级为I和II级的临床试验。在统计分析过程中,我们排除了所有对I检验有负面影响的研究,以获得更可靠的结果。对于方法学质量评估,我们参考PEDro评分。通过所有比较的漏斗图评估发表偏倚的风险。
PEDro评分显示方法学质量评估良好。漏斗图检测到发表偏倚的风险非常低。本研究纳入36篇文章,共计4052例患者和4884例手术。两组的平均随访期为3.39年。ROM的总体估计效应为PS组比CR组有利2.18°。总体WOMAC显示结果有利于PS组。KSCS的总体估计效应在CR组高0.02%。KSFS的总体估计效应为PS组有利2.09%。关于手术时长,估计效应为CR组比PS组短6.87分钟。两组在膝前疼痛、膝关节不稳定或翻修率方面未报告差异。
两种假体植入物均被证明是治疗终末期膝关节退变的安全可行方案。PS植入物在膝关节活动范围和手术时间延长方面有改善。在所分析的评分方面未发现临床相关差异。未检测到并发症方面的统计学显著差异。