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How I treat… alcohol-related liver disease.我如何治疗…酒精性肝病。
Clin Med (Lond). 2019 Jan;19(1):43-46. doi: 10.7861/clinmedicine.19-1-43.
2
Current treatment options for alcohol-related liver disease.酒精相关性肝病的治疗选择。
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Alcohol-related liver disease. Clinical practice guidelines. Consensus document sponsored by AEEH.酒精性肝病。临床实践指南。由AEEH赞助的共识文件。
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Early Liver Transplantation for Severe Alcoholic Hepatitis.早期肝移植治疗重症酒精性肝炎。
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ACG Clinical Guideline: Alcoholic Liver Disease.ACG 临床指南:酒精性肝病。
Am J Gastroenterol. 2018 Feb;113(2):175-194. doi: 10.1038/ajg.2017.469. Epub 2018 Jan 16.
8
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本文引用的文献

1
Corticosteroids Reduce Risk of Death Within 28 Days for Patients With Severe Alcoholic Hepatitis, Compared With Pentoxifylline or Placebo-a Meta-analysis of Individual Data From Controlled Trials.皮质类固醇与己酮可可碱或安慰剂相比可降低重症酒精性肝炎患者 28 天内的死亡率:来自对照试验的个体数据的荟萃分析。
Gastroenterology. 2018 Aug;155(2):458-468.e8. doi: 10.1053/j.gastro.2018.05.011. Epub 2018 May 5.
2
The prognostic value of acute-on-chronic liver failure during the course of severe alcoholic hepatitis.慢性加急性肝衰竭对重症酒精性肝炎病程的预后价值。
J Hepatol. 2018 Aug;69(2):318-324. doi: 10.1016/j.jhep.2018.02.022. Epub 2018 Mar 8.
3
Early liver transplantation for severe alcoholic hepatitis: moving from controversy to consensus.早期肝移植治疗重症酒精性肝炎:从争议走向共识。
Curr Opin Organ Transplant. 2018 Apr;23(2):229-236. doi: 10.1097/MOT.0000000000000507.
4
Transplanting Patients with Alcohol-related Liver Disease in the National Health System: New Rules and Decisions.国家卫生系统中酒精性肝病患者的移植:新规则与决策
Alcohol Alcohol. 2018 Mar 1;53(2):145-150. doi: 10.1093/alcalc/agx103.
5
Alcohol Use after Liver Transplantation is Independent of Liver Disease Etiology.肝移植后饮酒情况与肝脏疾病病因无关。
Alcohol Alcohol. 2016 Nov;51(6):698-701. doi: 10.1093/alcalc/agw032. Epub 2016 Jun 6.
6
Response to the NCEPOD report: development of a care bundle for patients admitted with decompensated cirrhosis-the first 24 h.对NCEPOD报告的回应:为失代偿期肝硬化入院患者制定护理套餐——最初24小时
Frontline Gastroenterol. 2016 Jan;7(1):16-23. doi: 10.1136/flgastro-2014-100491. Epub 2014 Dec 2.
7
Comparative Effectiveness of Pharmacological Interventions for Severe Alcoholic Hepatitis: A Systematic Review and Network Meta-analysis.药物干预治疗重症酒精性肝炎的疗效比较:系统评价和网络荟萃分析。
Gastroenterology. 2015 Oct;149(4):958-70.e12. doi: 10.1053/j.gastro.2015.06.006. Epub 2015 Jun 16.
8
Prednisolone or pentoxifylline for alcoholic hepatitis.泼尼松龙或己酮可可碱治疗酒精性肝炎。
N Engl J Med. 2015 Apr 23;372(17):1619-28. doi: 10.1056/NEJMoa1412278.
9
Nutritional therapy in cirrhosis or alcoholic hepatitis: a systematic review and meta-analysis.肝硬化或酒精性肝炎的营养治疗:系统评价与荟萃分析。
Liver Int. 2015 Sep;35(9):2072-8. doi: 10.1111/liv.12798. Epub 2015 Feb 15.
10
Prognosis of treated severe alcoholic hepatitis in patients with gastrointestinal bleeding.治疗后伴有胃肠道出血的重症酒精性肝炎患者的预后。
J Hepatol. 2015 Apr;62(4):816-21. doi: 10.1016/j.jhep.2014.11.003. Epub 2014 Nov 11.

我如何治疗…酒精性肝病。

How I treat… alcohol-related liver disease.

机构信息

Imperial College Healthcare NHS Trust, London, UK

Imperial College Healthcare NHS Trust, London, UK.

出版信息

Clin Med (Lond). 2019 Jan;19(1):43-46. doi: 10.7861/clinmedicine.19-1-43.

DOI:10.7861/clinmedicine.19-1-43
PMID:30651244
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6399631/
Abstract

Age-standardised mortality from liver disease in the United Kingdom has risen by 400% since 1970, with three-quarters of deaths from alcohol-related liver disease (ARLD). The 2013 National Confidential Enquiry into Patient Outcome and Death report found that only 47% of the patients dying in hospital from liver disease experienced 'good' care. We discuss common complications in the care of patients with ARLD and the evidence-based best practice that can improve patient outcomes, with a focus on the initial management of patients presenting acutely to the medical take.

摘要

自 1970 年以来,英国因肝病导致的标准化死亡率上升了 400%,其中四分之三的死亡病例与酒精性肝病(ALD)相关。2013 年国家患者结局和死亡机密调查显示,仅有 47%的在院肝病死亡患者得到了“良好”的治疗。我们讨论了在 ALD 患者护理中常见的并发症,以及可以改善患者预后的基于证据的最佳实践,重点关注急性就诊患者的初始管理。