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破裂性脑动脉瘤作为多囊肾病的首发表现:一例病例报告及文献复习

Ruptured Berry Aneurysm as the initial presentation of Polycystic Kidney Disease: A case report and review of literature.

作者信息

AlNuaimi Dana, AlKetbi Reem, AlFalahi Afra, AlBastaki Usama, Pierre-Jerome Claude

机构信息

Department of Radiology, Rashid hospital, Dubai, UAE.

Department of Radiology, Ackershus University hospital, lorenskog, Norway.

出版信息

J Radiol Case Rep. 2018 Sep 30;12(9):1-8. doi: 10.3941/jrcr.v12i9.3448. eCollection 2018 Sep.

Abstract

Intra-cranial saccular aneurysms, also known as Berry aneurysms, have a well-known association with autosomal dominant polycystic kidney disease (ADPKD). Aneurysmal rupture can be the initial presentation of the disease. ADPKD has two types of gene mutations: PKD1 and PKD2. The latter one is of a milder form presenting later in life. Imaging plays a crucial role in the diagnosis and assessment in order to provide adequate management of these patients however, there are no official standardized guidelines established for screening of these intracranial aneurysms.

摘要

颅内囊状动脉瘤,也称为浆果样动脉瘤,与常染色体显性多囊肾病(ADPKD)有着众所周知的关联。动脉瘤破裂可能是该疾病的首发表现。ADPKD有两种基因突变类型:PKD1和PKD2。后者病情较轻,发病较晚。影像学在诊断和评估中起着关键作用,以便为这些患者提供适当的治疗,然而,目前尚无针对这些颅内动脉瘤筛查的官方标准化指南。

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