Tsuchimoto S, Katayama T, Itoh K, Kusumoto K, Satoh Y, Hakozaki H, Natori T
Dept. of Surgery, Hokkaido University School of Medicine.
Hokkaido Igaku Zasshi. 1988 Jul;63(4):545-51.
Primary malignant lymphoma of gastrointestinal tract is relatively rare and the most of it are seen in stomach or small intestine, and in Japan only 130 cases of primary large intestinal malignant lymphoma were reported from the accumulating results of the postoperative cases in the 11th Congress of the Japanese Research Society for Cancer of the Colon and Rectum. This paper describes the case report of the primary malignant lymphoma originated from the cecum, and the review of the literature. The patient was 63 year-old female, who came to this hospital for slight fever and right lower abdominal pain that was gradually increasing. After the investigation by using barium enema and the intrapelvic CT, cecum tumor was detected. The ileocecal excision was performed, and revealed the 4 X 4.5 cm tumorous type lesion of which surface was slightly irregular. Histopathologically the tumor was follicular lymphoma (partial type), medium sized cell type by the Lymphoma-leukemia Study Group (LSG) classification. After discharge, cyclophosphamide was administered by 100 mg/day for six weeks, and the sign of the recurrence has not been observed.
原发性胃肠道恶性淋巴瘤相对少见，大部分发生于胃或小肠，在日本，根据日本结肠直肠癌研究学会第11届大会上术后病例的累积结果，仅报告了130例原发性大肠恶性淋巴瘤。本文描述了一例起源于盲肠的原发性恶性淋巴瘤病例报告及文献复习。患者为63岁女性，因低热及逐渐加重的右下腹痛前来我院就诊。经钡灌肠及盆腔CT检查，发现盲肠肿物。行回盲部切除术，术中见一4×4.5cm大小的肿瘤型病变，表面略不规则。组织病理学检查显示肿瘤为滤泡性淋巴瘤（部分型），根据淋巴瘤白血病研究组（LSG）分类为中等大小细胞型。出院后，给予环磷酰胺100mg/天，持续六周，未观察到复发迹象。
