Yong Bryan, Power David A
Clinical School, University of Melbourne, Parkville, Victoria, Australia.
Department of Nephrology, Austin Health, Studley Road, Heidelberg 3084, Victoria, Australia.
Case Rep Nephrol. 2018 Dec 17;2018:3273695. doi: 10.1155/2018/3273695. eCollection 2018.
Pulmonary-renal syndrome is characterised by acute kidney injury, haematuria, and haemoptysis and is a well-recognised presentation of diseases such as ANCA vasculitis that require urgent immunosuppression.
A patient presented with a brief history of haemoptysis, acute renal failure, microscopic haematuria, and severe hypertension. The diagnosis was initially not clear so he was treated with antihypertensives, renal replacement therapy, and immunosuppression. Renal biopsy subsequently showed evidence of malignant hypertension. Autoantibodies were uniformly negative.
This case demonstrates that malignant hypertension can present as pulmonary-renal syndrome.
肺肾综合征的特征为急性肾损伤、血尿和咯血,是抗中性粒细胞胞浆抗体(ANCA)血管炎等疾病的一种公认表现,这些疾病需要紧急免疫抑制治疗。
一名患者出现咯血、急性肾衰竭、镜下血尿和严重高血压的简短病史。最初诊断不明确,因此对他进行了抗高血压治疗、肾脏替代治疗和免疫抑制治疗。随后肾活检显示有恶性高血压的证据。自身抗体均为阴性。
本病例表明恶性高血压可表现为肺肾综合征。